Aromatic Amino Acids Are Critical for Stability of the Bicoid Homeodomain. Subramaniam V,Jovin T M,Rivera-Pomar R V. Journal of Biological Chemistry . 2001Subramaniam, V., Jovin, T.M., and Rivera-Pomar, R.V. 200
Amino acids are not only important for protein synthesis but also serve as precursors for hormones, coenzymes, alkaloids, cell wall polymers, porphyrins, antibiotics, nucleotides, pigments, and neurotransmitters.150 A deficiency of one amino acid may result in a negative nitrogen balance (Figure 9)...
Critical amino acid positions for the insecticidal activity of Vip3Af1. The Vip3Af1(WT) sequence is represented by the pale blue bar. The dashed region was not subjected to alanine scanning; dark blue segments in the protein bar are the regions where these critical positions are clustered. Abo...
Many drug formulations containing small active molecules are used for the treatment of coronary artery disease, which affects a significant part of the world’s population. However, the inadequate profile of these molecules in terms of therapeutic efficacy has led to the therapeutic use of protein a...
Amino acids are considered the most critical regulator of mTORC1 because growth factors alone cannot activate the kinase efficiently during amino acid deprivation7. In addition to its role in promoting anabolic pathways, mTORC1 represses catabolic processes like macroautophagy (hereafter referred to as ...
Alkaline hydrothermal systems have received considerable attention as candidates for the origin and evolution of life on the primitive Earth. Nevertheless, sufficient information has not yet been obtained for the thermodynamic properties of amino acids, which are necessary components for life, at high te...
“At first, this made no sense, because if these amino acids came from contamination by terrestrial life, both amino acids should have large left-handed excesses, because both are common in biology,” says Glavin. “However, a large left-hand excess in one and not the other tells us that...
The system L amino acid transporter (LAT) has an important role in the transport of various amino acids, and there have been reports about the relation of this system to cancer. Although LATs are highly expressed in the kidneys, little is known about their influence on human renal cancer. ...
2. Amino Acids a. Deficiency. Deficiencies of specific amino acids are rare, although many diets can be relatively deficient in certain groups of amino acids. For example, many corn-based diets are limited in lysine and tryptophan content, whereas peanut and soy-based diets are often low in ...
Rhizobia are positively chemotactic to a range of molecules released by the host plant after seed germination, including sugars, amino acids, various dicarboxylic acid anions (such as succinate, malate, and fumarate), and aromatic compounds, including shikimate, quinate, protocatechuate, vanillate, ...