20种氨基酸的功能（The function of 20 amino acids）Effects of amino acids on human body Glycine (GLY)1, reduce blood cholesterol levels, prevention and treatment of hypertension 2, reduce blood sugar levels, prevention and treatment of diabetes 3, can prevent blood clots, thrombosis 4, improve ...
Natural proteins are composed of 20 proteinogenic amino acids and their post-translational modifications (PTMs). However, due to the lack of a suitable nanopore sensor that can simultaneously discriminate between all 20 amino acids and their PTMs, direct sequencing of protein with nanopores has not...
Efforts to sequence single protein molecules in nanopores1,2,3,4,5have been hampered by the lack of techniques with sufficient sensitivity to discern the subtle molecular differences among all twenty amino acids. Here we report ionic current detection of all twenty proteinogenic amino acids in an...
Amino acid, any of a group of organic molecules that consist of a basic amino group, an acidic carboxyl group, and a unique organic side chain. The term amino acid is short for α-amino [alpha-amino] carboxylic acid. Examples of amino acids include glyci
1.1 Amino acids Amino acids are the building blocks of proteins. Even though around 190 amino acids are known today, only 20 different amino acids are required by humans to synthesize all necessary proteins. All these 20 amino acids are alpha-amino acids, given that both functional groups, the...
Recently, the bond lengths of the molecular components of nucleic acids and of caffeine and related molecules were shown to be sums of the appropriate covalent radii of the adjacent atoms. Thus, each atom was shown to have its specific contribution to the bond length. This enabled establishing ...
All amino acids tested under 195 mm Hg pCO2/435 mOsm/kg (50% growth inhibition) restored the specific growth rate () in hybridoma cells to that observed under control conditions (40 mm Hg/320 mOsm/kg). Addition of each amino acid resulted in an increase in the consumption rate and ...
This process has several advantages compared to the other methods. First of all, it produces only thel-form amino acids avoiding furtherpurificationsteps. Another important factor is that it can be operated at mild conditions preventing product degradation (Ugimoto, 2010). Furthermore, the maintenanc...
The established method enables quantitative analysis of 22 amino acids, all 20 proteinogenic amino acids, ornithine and citrulline. Cysteine is measured as cystine. The combination of precipitation, derivatization and chromatographic separation effectively avoids ion suppression and coelution. Simultaneous ...
Using the interaction between the α-amine group and α-carboxyl group of amino acids and the copper–nanopore complex to generate current blockade, we developed a copper-ion-functionalized MspA nanopore. This nanopore sensor enables the identification of all 20 proteinogenic amino acids, 2 amino ...