Elango R, RO Ball and PB Pencharz: Amino acid requirements in humans: with a special emphasis on the metabolic availability of amino acids. Amino Acids 37, 19-27 (2009)Elango, R., R. O. Ball, and P. B. Pencharz. 2009. Amino acid re- quirements in humans: With a special ...
There are 21 standard proteinogenic amino acids in humans 20 are encoded for protein synthesis by the genetic code Selenocysteine is incorporated via a mechanism known as translational recoding Properties Essential or nonessential Essential vs. nonessential amino acids GroupAmino acidSynthesisCatabolic ...
In experimental animals, a high protein diet has been shown to accelerate end-stage renal disease by inducing glomerular hyperperfusion. In this study, we found that intravenous administration of amino acid, used as one component of parenteral nutrition, to normal volunteers resulted in a significant...
meaning they are not normally required in the diet, but must be supplied exogenously when not being synthesized it in adequate amounts in body (Fürst and Stehle, 2004). In humans, the essentialamino acidneeds for netprotein depositionare a minor portion of the total amino acid requirement (...
The wide range of amino acid functions, including amino acid synthesis, breakdown, and transport, has provided numerous targets for the development of drugs. Amino acid-degrading enzymes such as arginase and asparaginase have been shown to exert antitumor effects in preclinical and clinical settings;...
from their precursors of the central metabolism (Figure 2). The relative uses of amino acid biosynthetic pathways vary widely amongspeciesbecause different synthesis pathways have evolved to fulfill unique metabolic needs in different organisms. Although some pathways are present in certain organisms, ...
Surveys the Toll-like receptor 4 protein (TLR4) in the complete coding region (2.4 kb) in 348 individuals from several population samples. Function of TLR4 in detecting Gram-negative pathogens; Spectrum of allele frequencies for amino acid variants; Contribution of genetic variants to disease suscep...
Theanine is a unique amino acid found almost solely in tea plants and the main component responsible for the exotic taste of ‘green’ tea. It was found that L-theanine administered intraperitoneally to rats reached the brain within 30 min without any metabolic change. Theanine also acts as a...
Juneja L R,Chu D C,Okubo T,et al.L-theanine-a unique amino acid of green tea and its relaxation effect in humans.Trends in Food Science and Technology. 1999Juneja L R,Chu D C,Okubo T,et al.L-theanine-a unique amino acid of green tea and its relaxation effect in humans. Trends...
In our analysis the exponent was also robust to halving the data sets, and needed an alternative interpretation relevant for covariance. Considering amino acid conservation (ϕ) as a surrogate for their fitness, we developed a fitness based model36. The model uses two distributions derived from...