Unknown amino acid (any amino acid)XRandom codon Translation stop*TAA TAG TGA Gap of indeterminate length--- Unknown character (any character or symbol not in table)??? Data Types:double|char|string Nucleotide alphabet, specified as"DNA"or"RNA". If"DNA", the function usesA,C,G, andT...
Amino acid-nucleotide interactions on an insoluble solid support. I. A simple model of the amino acid acceptor terminus of a tRNA.Merrifield's 2 chloromethylated polystyrene resinMerrifield's 2 chloromethylated polystyrene resinAdenosine 5′-monophosphate (AMP) can be attached to Merrifield resin [...
Single nucleotide polymorphisms (SNPs) within the MTHFD2-controlled cluster associate with CAD. The MTHFD2-controlled cluster redirects metabolism to glycine synthesis to replenish purine nucleotides. Since endothelial cells secrete purines in response to oxPAPC, the MTHFD2-controlled response maintains ...
Accumulation of uric acid crystals in the joints, possibly caused by another genetic deficiency, results in gout. Enzymes of the nucleotide biosynthetic pathways are targets for an array of chemotherapeutic agents used to treat cancer and other diseases. ...
1972. Initial nucleotide frequencies of bacterial RNA synthesized during amino acid starvation or changes of carbon source. Nature N. Biol. 238:231-233.Konrad, M., J. Toivonen, and D. P. Nierlich. 1972. Initial nucleotide frequencies of bacterial RNA synthesized during amino-acid starvation or...
amino acid in response to a pre-maturestop codonas well asmissensesuppressor tRNAs that decode a lethal sense codon mutation with a non-cognate amino acid to rescue cell growth. Nucleotide changes that convert a tRNA into a missense suppressor map to distinct regions of the tRNA molecule. The...
We present TranslatorX, a web server designed to align protein-coding nucleotide sequences based on their corresponding amino acid translations. Many comparisons between biological sequences (nucleic acids and proteins) involve the construction of multiple alignments. Alignments represent a statement regardin...
There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes. A simple sequence editor (SSE) was developed to crea
9. A cell comprising a recombinant expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide encoding a potassium channel at least 80% identical to SEQ ID NO:2, wherein the amino acid of the potassium channel corresponding to amino acid number 277 of...
to probe systematically the influence of nucleobase, nucleotide position and amino acid composition on the cross-linking profile. This reveals that cross-linking only occurs with guanosine or uridine at three of the seven nucleotide positions, and only when bases are stacked to aromatic amino acid ...