Amino acid side chainFTIR spectroscopyProtein microarraysProtein spectroscopySecondary structurePrediction of protein secondary structure from FTIR spectra usually relies on the absorbance in the amide I–amide
Leucine (Leu or L) ((S)-2-amino-4-methyl-pentanoic acid) is a neutral, aliphatic amino acid with the formula HOOCCH(NH2)CH2CH(CH3)2 and with a hydrocarbon side chain, Leu is classified as a hydrophobic (nonpolar) amino acid.11,150 Lysine (Lys or K) (2,6-diaminohexanoic acid) is...
Stepwise regression analysis proved that the strength of interaction is influenced only by the lipophilicity of the amino acid side-chain and the pK value of the second carboxyl group. This finding indicates that the amino acid side-chain is directed towards the adenine, and the polar head group...
Amino acids contain a central carbon atom (Cα), which is attached to a hydrogen atom, an amino group (NH2), and a carboxyl group (COOH) as shown in Figure 1.1. The letter R in Figure 1.1 indicates the presence of a side chain, which distinguishes each amino acid. Sign in to ...
Theamino_acidmodule contains a variety of physical/chemical properties for both single amino residues and interactions between pairs of residues. Single residue feature tables are parsed intoStringTransformerobjects, which can be treated as dictionaries or will vectorize a string when you call their met...
The polarity of the amino acid is based on whether the side chain is hydrophobic or hydrophilic. Moreover, the charge of the side chain is determined at physiological conditions (i.e., at pH 7). Aside from these, nonpolar amino acids can be further cl...
As has been shown in literature, this conformational preference of the backbone has a significant influence on the flexibility of the peptide substrate chain. Following our results, this property seems to have significant influence on the recognition of the amino acid side groups by the enzyme ...
Proteins are polymers of amino acids. Draw a general diagram of an amino acid. Make sure to note the part of the general structure that varies to make the different amino acids. Which amino acid has a side-chain with a pK_a value less than 5? (a) Histidine (...
Glycine is a simple amino acid that does not have a hydroxyl group as a side chain as serine does; however, it cannot be completely excluded that glycine cannot form a non-covalent bond with sialic acid. In addition to serine, several amino acids are involved in the hydrophobic pocket in ...
The amino acid composition is determined on protein hydrolysates obtained after 24, 48, and 72 hours of acid treatment. The content of amino acids with bulky aliphatic side chains such as isoleucine, leucine, and valine, which undergo slow hydrolysis, is calculated from an extrapolation of the ...