Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth, differentiation and function. Amino acid metabolism disorders have been linked with a number of pathological conditions, including metabolic diseases, cardio...
Table of common amino acid abbreviations and properties NameThree letter codeOne letter codeMolecular WeightMolecular FormulaResidue FormulaResidue Weight (-H2O)pKapKbpKxpl AlanineAlaA89.10C3H7NO2C3H5NO71.082.349.69–6.00 ArginineArgR174.20C6H14N4O2C6H12N4O156.192.179.0412.4810.76 ...
Beta amino acid refers to a 111 amino acid chain that confers biological activity in proteins. It is noncovalently linked to an alpha chain and is glycosylated, particularly with sialic acid. AI generated definition based on: Reference Module in Biomedical Sciences, 2015 ...
Furthermore, due to the α-keto acid-, ammonia-, and highly damaging H2O2-induced oxystress nature of D-AA oxidase activity, this enzyme has been utilized in gene-directed enzyme prodrug therapies that target cancer. Oxidative damage to DNA, proteins and lipids on tumor cells promotes their ...
Aminoacylation, the attachment of an amino acid to a tRNA, is typically a two-step process catalyzed by the aminoacyl-tRNA synthetases. The first step, termed ‘activation’, is the formation of an aminoacyl-AMP (aminoacyl-adenylate) on the enzyme through the hydrolysis of adenosine triphosphate...
et al. Branched-chain amino acid-enriched nutrients stimulate antioxidant DNA repair in a rat model of liver injury induced by carbon tetrachloride. Mol. Biol. Rep. 39, 10803–10810 (2012). CAS PubMed Google Scholar Kuwahata, M. et al. Supplementation with branched-chain amino acids atten...
However, evidence of long-term impacts of maternal glycemic status on offspring amino acid (AA) profiles is scarce. We aimed to investigate the association between maternal antenatal glycaemia and offspring mid-childhood amino acid (AA) profiles, which are emerging cardiometabolic biomarkers. Methods ...
6)L-氨基酸氧化酶(L-Amino Acid Oxidase)有蛋白污染:电泳前酚抽提去除蛋白; 7) DNA变性:电泳前勿加热,用20mM NaCl缓冲液稀释DNA。 2.不规则DNA带迁移 1)对于λ/Hind III片段cos位点复性电泳前于65℃加热DNA 5分钟,然后在冰上冷却5分钟; 2)电泳条件不合适:电泳电压不超过20V/cm;温度<30℃;经常更换电泳缓冲...
No such peak was observed in reactions that lacked either the DNA template or acyl-tRNA, confirming templated ribosomal initiation with α-thio acid 13, 2-benzylmalonic acid (14) and N-formyl-l-α-amino acid 15. Two peaks of identical mass were observed in the extracted ion chromatogram (...
Table 1 The structural information for cytarabine-5′-triphosphate and our designed amino acid-carbohydrate based structures. Full size table To find the best conformer for CNP (which will be used for MD calculations), we used Auto Dock Vina, which suggested nine conformers. Figure4illustrates th...