(a) Common structure of α-amino acids, position of the α-carbon is labeled; ‘R’ represents any number of possible chemical structures, which may be as simple as a single hydrogen atom (–H, as in the amino acid glycine) or more complex chemical groups, as in (b); (b) Examples...
Each receptor recognizes the characteristic features, or epitope, of an amino acid molecule, including (1) hydrocarbon chain length, (2) difference in functional groups, and (3) position of functional groups. Although the three receptor types are quite specific under the natural condition, because...
Amino acid, any of a group of organic molecules that consist of a basic amino group, an acidic carboxyl group, and a unique organic side chain. The term amino acid is short for α-amino [alpha-amino] carboxylic acid. Examples of amino acids include glyci
The invention concerns an amino-acid unit for use in peptide synthesis in which a hydrogen atom of the amino group entering into a peptide bond is protected by a temporary amino protection group which can be cleaved under non-acid conditions. It is characterized in that the second hydrogen ...
covering low and high organic film concentrations and therefore effectively averaging the signal. In panel B) the ratios of the two amino acid fragments at each position are displayed and compared to the average ratio obtained from co-added data. Most of the individual ratios are within the 1σ...
theeffectofaminoacidconfigurationonbiodistributionpeptidenanofiber 系统标签: 多肽纳米纤维构型氨基酸biodistributionpeptide 天津医药2014年2月第42卷第2期氨基酸构型对多肽纳米纤维体内分布的影响*徐宏艳张玉民杨翠红刘金剑褚丽萍闫玉军刘鉴峰宋娜玲△【摘要】目的比较由L构型和D构型氨基酸自组装形成的纳米纤维在体内分布的差异...
Secondary configuration provides useful information to understand the local 3D structure of proteins. This structure can be studied by looking at the amino acid contributions to local protein structures, namely, helix (ph), strand (pe) and coil (pc). Therefore, we run the SPIDER2 tool [23] ...
At the pHi, an amino acid in solution subjected to an electrical field will not move toward any of the electrodes. In dicarboxylic and diaminated amino acids, there is an additional ionizable group. For example, aspartic acid in a strong acid medium is fully protonated. In contrast, if ...
30. A method for incorporating a non-natural amino acid into a target polypeptide at one or more specified position(s), the method comprising the steps of: (1) determining the structural change in the polypeptide for incorporation of a non-natural at one specific position in the polypeptide;...
wherein the configuration of the amino-terminal aspartyl or glutamyl group is L; and wherein the configuration at the carbon to which R1is bonded is L, if n is 0, and D, if n is 1 or 2 and R1is methyl, which comprises: (i) reacting a strong acid salt of a compound of formula...