All reactions were conducted under condition [C] (H2O/TFE (1:1), DIPEA, rt) at 5.0 mM concentration. a Extension of 27. Isolated yield over two steps in one pot. Stereochemistry of the double modification products has not been determined. b Possible reaction pathways of the isoindolin-...
Amines are a class of compounds of essential importance in organic synthesis, pharmaceuticals and agrochemicals. Due to the importance of chirality in many practical applications of amines, enantioselective syntheses of amines are of high current interes
The reactions of the bromocarbyne complex [Mo(CBr)(CO)2{HB(pzMe2)3}] (pz = pyrazol-1-yl) with a range of secondary and heterocyclic amines have been investigated and found in each case to proceed via simple nucleophilic halide substitution to provide N-functionalized carbyne derivatives, som...
Facile and efficient synthesis of a new class of bis(3′-indolyl)pyridine derivatives via one-pot multicomponent reactions. Tetrahedron Lett. 2008, 49, 1777-1781. Molecules 2011, 16 3739 16. Ibrahim, H.; Makhseed, S.; Abdel-Motaleb, R.M.; Makhloof, A.A.; Elnagdi, M.H. Utility...
of example as starting materials, including ethylene glycol. It cannot be deduced from the document that the catalyst described would in the process step of the conversion of monoethylene glycol into monoethanolamine display an increased selectivity compared to the subsequent reactions of monoethanolamine...
The amount of DMS used for all reactions is determined by perchloric acid titration (“PAT” value) of the esteramine. The esteramine is charged to a round-bottom flask equipped with a reflux condenser, thermocouple/heating mantle, and nitrogen inlet. The sample is heated to 65° C. if ...
All reactions were carried out under an air atmosphere. Reagents used in the reactions were all purchased from commercial sources and used without further purification. Unless otherwise specified, NMR spectra were recorded in CDCl3or DMSO‑d6on a 500 MHz (for1H), 126 MHz (for13C) spectromete...
All of the reactions involving air- or moisture sensitive compounds were carried out in an inert atmosphere box (O2 < 1 ppm) or by standard Schlenk techniques under Ar. Glassware was oven dried or flame dried prior to use. All commercial reagents were used as received without further purificat...
Generally, reactions of this ring with difunctional reagents may lead to different types of prod- ucts such as open chain bridged, spiro, ansa, oligomer, polymer or their mixtures. The formation of these products depends on many factors such as the chain length of the difunctional reagents, ...
These reactions were carried out in toluene/water solutions in the presence of polymers and their mono- meric analog (benzoguanamine and N,N,N',N'-tetra- methylbenzoguanamine). Catalyst + +n-C8 H 17Br KSCN ---> n-C8 H 1 7 SCN KBr The results are summarized in Table IV. As can...