Valvular heart disease associated with the use of some anorectic agents such as fenfluramine and dexfenfluramine has been reported. Possible contributing factors include use for extended periods of time, higher than recommended dose, and/or use in combination with other anorectic drugs. However, no...
Hyperphosphatemia frequently accompanies diseases associated with inadequate renal function, hypoperathyroidism, and certain other medical conditions. Hyperphosphatemia is typically defined as possessing a serum phosphate level of over about 6 mg/dL. The condition, especially if present over extended perio...
which is produced via a lateral branch of the IDO1 pathway in DCs, but also at high levels in lymphatic endothelial cells (LEC) and human tumor cell lines. 3-HKA inhibits the activation of pro-inflammatory STAT1 and NF-kB pathways in mouse and human DCs and has therapeutic...
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A polymerization method may be a one-shot method in which all raw materials are mixed and reacted at once, or a prepolymer method in which a prepolymer is first prepared and then chain extended. A suitable amount of a reaction rate regulator such as an organic acid (e.g. acetic acid, ...
Fluorescent probes typically require a rapid enhancement of fluorescence upon contact with the target substance, followed by a sustained emission over an extended period of time. Consequently, the reaction time between the probe and L-Lys has been investigated. Taking (L,R)-1 as an example, the...
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(A) Constellation plot of the selected 19 SMs based on their two-dimensional structural similarities. In bold: SMs effective against nineSalmonellaserovars. The root of the tree is represented by the circle within the plot. (B) Skeletal chemical formula of the selected five SMs. SMs were ...
As a result of this extended hydrogen-bond network, the ions are linked into a complex three-dimensional array.Okeke, U.Department of ChemistryGultneh, Y.Butcher, R.J.Acta Crystallographica Section E: Crystallographic Communications
In A, the molecule adopts an extended conformation approximating to C2 symmetry, whereas the two independent molecules of form B display a folded hair-pin conformation with pseudo-mirror symmetry [torsion τ (C-S···S'-C') and intercentroid distance dIC of the aromatic rings in A: 173.2...