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The meaning of AMIDE is an inorganic compound derived from ammonia by replacement of an atom of hydrogen with another element (such as a metal).
Application of Nimesulide[46]structure using the analog-baseddrug designapproach with an aim of searching for new potential multi-target agents with dual inhibition ofheat shock proteinfunction (HSP27) and tubulin was reported by Jaragh-Alhadad et al.[47]. The function ofHSP27is up-regulated i...
3. A phosphoramidite monomer with an MMT-protected 5′-amino group, either LNA 1040 or deoxythymidyl 11, is added to the oligonucleotide, and the amine is deprotected using trichloroethanoic acid. An LNA-acid (or DNA-acid50) monomer is coupled to the free amine using PyBOP activating ...
The formation of cis-β-lactams (8) and trans-β-lactams (9) with (9,10-dihydrophenanthren-3-yl)amine can be explained through isomerization of the enolates (Scheme 3.5, A to B). The electron-withdrawing dihydrophenanthrene group at the nitrogen can stabilize the iminium ion through a ...
1. Nomenclature of The Amide Functional Group: Primary, Secondary, and Tertiary Amides “Amides” are what we call an amine that has a single attached carbonyl group. The amide functional group is to amines as esters are to alcohols. Confusingly, the word “amide” is also used to refer...
The trisubstituted NH-amide-sulfoxonium ylide smoothly underwent the insertion reaction with amine-borane adduct, furnishing the desired product 92 in 79% yield. The reaction tolerated a variety of functional groups, including methyl (80 and 87), halides (81–83, and 89), alkenyl (84 and 90)...
Examples of amides include carboxamides, sulfonamides, and phosphoramides. Nylon is a polyamide. Several drugs are amides, including LCD, penicillin, and paracetamol. Uses of Amides Amides may be used to form resilient structural materials (e.g., nylon, Kevlar). Dimethylformamide is an important ...
α-boryl amides in moderate to excellent yields (79–94). The trisubstituted NH-amide-sulfoxonium ylide smoothly underwent the insertion reaction with amine-borane adduct, furnishing the desired product92in 79% yield. The reaction tolerated a variety of functional groups, including methyl (80and87)...
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