"AMG 133 was designed based on preclinical and human genetic data that strongly suggest GIPR inhibition as a strategy for weight loss, especially in combination with GLP-1 agonism," saidDavid M. Reese, M.D., executive vice president of Research and Development atAmgen. "We are...
AMG 513当前未公布靶点或作用机制,据clinicaltrials.gov网站显示,安进在2024年9月注册了AMG 513治疗减重的I期临床试验。试验预计在2026年3月完成,采用皮下注射或静脉注射的给药方式,旨在全面评估AMG 513在肥胖患者中的安全性和耐受性。 4. 诺和诺德一款新药II期临床失败,曾斥资11亿美元引进 2月5日,诺和诺德公布...
Phase 1 clinical trial of AMG 340, a prostate-specific membrane antigen (PSMA)-targeted T-cell engager with a novel low-affinity CD3 binding domain designed to mitigate toxicity for the treatment of metastatic castration-resistant prostate cancer (mCRPC)....
[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164. 其他产品列表: ...
Friberg for their support and contributions; all of the patients who participated in the AMG 510 first-in-human clinical trial; and the staff of Crystallographic Consulting and the Advanced Light Source at beamline 5.0.1 for their data collection support. The Berkeley Center for Structural Biology...
Trial InformationBone & Cancer Foundation