Sex differences are present in brain morphology, sex hormones, aging processes and immune responses. These differences need to be considered for proper modelling of neurological diseases with clear sex differences. This is the case for Alzheimer’s disease (AD), a fatal neurodegenerative disorder with...
Alzheimer’s Disease (AD) is a progressive neurodegenerative disease characterized by the loss of function of neurons and their consequent death [1]. Although AD is not a natural consequence of aging, it is generally seen in the elderly population [2]. The main symptoms encountered in Alzheimer...
Browse Figures Review Reports Versions Notes Abstract Alzheimer’s disease (AD) is a polygenic multifactorial neurodegenerative disease that, after decades of research and development, is still without a cure. There are some symptomatic treatments to manage the psychological symptoms but none of these...
Alzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting a growing number of elderly people. In order to improve the early and differential diagnosis of AD, better biomarkers are needed. Glycosylation is a protein post-translational modification that is modulated in the cour...
Finally, we formed a panel of rSNPs localized to the promoters of genes that contribute to the epigenetic landscape in AD and, thus, to the genetic predisposition for this disease. Keywords: Alzheimer’s disease; epigenetics; histone modification; chromatin remodeling; non-coding regulatory SNPs; ...
Alzheimer’s disease; MRI; PET; data fusion; vision transformer 1. Introduction 1.1. Background Alzheimer’s disease (AD) is a chronic neurodegenerative disease that gradually destroys brain cells, resulting in memory and thinking skill loss, as well as the eventual loss of the ability to ...
Alzheimer’s Disease; fermented foods; phytochemicals; soy isoflavones; ginsenosides; kimchi phytochemicals; neuroprotection; cognitive function 1. Introduction Worldwide, approximately 55 million people live with dementia, of which it is estimated that Alzheimer’s Disease (AD) and Alzheimer’s Disease-...
Alzheimer’s disease; mental health technology; digital devices; applications; sensors; virtual reality; empowerment1. Introduction Dementia is a neurological condition affecting approximately 50 million people worldwide [1]. Because of the aging population, it currently represents a social and health ...
Browse Figures Versions Notes Abstract Objective: The purpose of this meta-analysis was to examine the effects of physical activity (PA) on cognition and activities of daily living in adults with Alzheimer’s Disease (AD). Methods: Six electronic databases (MEDLINE, CINAHL, PsycArticles, SPORTDis...