Care in late-stage ADRD is demanding and requires substantial formal and informal resources. While most persons with ADRD at Global Deterioration Scale (GDS) stage 7 ADRD live in nursing homes, a majority of persons at GDS 5–6 live at home [3]. Moreover, persons with late-stage ADRD...
which may lead to an increase in viscosity4. Since there is no cure for AD, early diagnosis has been proposed as a crucial aspect of AD care. By
near plaques28. Fragments of amyloid and tau may in turn drive hyperplasticity through enhanced gene transcription29. Indeed, proteins increased in subtype 1 were enriched for the transcription factors REST (Padjusted = 0.018 × 10−13; Fig.1dand Supplementary Table7) and SUZ12 (Pa...
Care in late-stage ADRD is demanding and requires substantial formal and informal resources. While most persons with ADRD at Global Deterioration Scale (GDS) stage 7 ADRD live in nursing homes, a majority of persons at GDS 5–6 live at home [3]. Moreover, persons with late-stage ADRD...