Alternative splicing of this gene results in two transcript variants. en.wikipedia.org Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. en.wikipedia.org Alternative splicing is the basis for the structural and functional diver...
Using these structures as a guide, we generated and tested truncated versions of clone c2 to investigate the role of the conserved regions (Figure 2c). As expected, deletion of the conserved 5′-nonamer (min.3) or modifications which converted the cytosine-rich bulge to a loop (min.4) ...
Since the quality of the reference genome can also affect mapping efficiency, we repeated the mapping process for both the latest and the previous versions of the genome assemblies. For the pig species, we included five breeds and two reference genome versions: Sscrofa10.2 and Sscrofa11.1. ...
Note:The most recent version ofsalmonhas changed the way that transcriptome indexes are made. LABRAT does not currently support these versions (salmon >= 1.0.0), but will in the future. conda env create -f labratenv.yml This will create a conda environment called 'labrat' that contains ...
Through a process known as dosage compensa- tion, the transcription level of genes on the single X chro- mosome in males is doubled to match the level of their expression in females [20]. Previous microarray analysis of gene expression has shown that male-biased genes are depleted on the...
Following signatures are supported: re2.exec(buf) re2.test(buf) re2.match(buf) re2.search(buf) re2.split(buf[, limit]) re2.replace(buf, replacer) Differences with their string-based versions: All buffers are assumed to be encoded as UTF-8 (ASCII is a proper subset of UTF-8). ...
(NMD) caused by a premature termination codon (PTC)41,42. In humans, 85% of mRNAs studied are predominantly transcribed as a single, major isoform43. A combination of mass spectrometry and transcription profile analysis can help elucidate the roles of AS in gene expression regulation creating ...
apoptosis. CTCF-s activatesIFI6expression by disrupting CTCF chromatin insulator function within theIFI6gene, facilitating an abnormal long-range interaction between anIFI6distal enhancer and its promoter. Together, these findings demonstrate how alternatively spliced versions of important architectural ...
We found that mRNA levels of D1Pas1 and Ahnak were decreased, whereas the other transcripts were not modulated (Supplementary Figure S3). Interestingly, the peak sequences referring to the Chrng gene (Supplementary Table S1) were contained in the 3'UTR of a predicted but not yet verified ...
(Fig.1a). Surprisingly, for four of them there are several highly conserved paralogues scattered through the genome in different chromosomes, with the exception ofRiSP2. Only in two cases, more than oneSP7-likegene is found in the same chromosome (Fig.1b). Paralogues encode proteins that ...