Currently, the genetics or epigenetics signatures identified from “omic” datasets provide valuable resources for searching alternative targets of the Myc oncoprotein. Discovering the vulnerable and druggable nodes underlying Myc deregulation is pivotal for the alternative targeting of Myc for cancer treatme...
Currently, the genetics or epigenetics signatures identified from “omic” datasets provide valuable resources for searching alternative targets of the Myc oncoprotein. Discovering the vulnerable and druggable nodes underlying Myc deregulation is pivotal for the alternative targeting of Myc for cancer treatme...
Alternative Cancer Therapies and Biological Treatments We use our hearts and minds to support you. We focus on clarity, creativity and competence on your way to better health. Again and again we see solutions ‘off the shelf’, which are not our way of thinking and treating. ...
In almost all countries, CAM is important for CML patients and is widely used in addition to conventional leukemia treatment. Mostly, patients have to pay by themselves. General practitioners, herbalists, healers and naturopaths are the main sources for CAM treatments. Information on CAM is ...
C-NHEJ may account for translocation events in some specific situations such as during the recovery from early apoptotic DNA fragmentation [230], [231], [232], or in the pathogenesis of acute leukemias secondary to cancer treatments based on Topoisomerase-II (TopoII) inhibitors that frequently fe...
The differences in stomatal apertures between the two plants revealed different responses to drought treatments. Compared to Glycine max, Glycine soja exhibited a reduction in stomatal aperture size under drought conditions relative to normal conditions (Fig. 1F). These results may be related to ...
preventive efficacies of all concentrations of Eucalyptus oil were significantly (p<0.001) higher than that of M. spicata oil and chlorhexidine. Results suggest E. camaldulensis and M. spicata significantly retard biofilm formation that can contribute to the development of novel anticaries treatments....
the normalization of the tumor vasculature has emerged as a new therapeutic strategy. Vascular normalization, by restoring proper tumor perfusion and oxygenation, could limit tumor cell invasiveness and improve the effectiveness of anticancer treatments. In this review, we investigate the mechanisms involve...
The following naturally obtained drugs are used as anticarcinogenic treatments. Molecular modeling of Strychnos alkaloids docked to a homolog of P-gp was employed to optimize ligand protein interactions with increased affinity to P-gp. The compounds, which were evaluated by computational-based design,...
ReCiPe for CML-2001 human toxicity, non-carcinogens (IMPACT 2002+): CAS-N and MBR had the highest value among the majority of techniques, while the proposed alternative had the lowest value. Figure 10. A comparison between the proposed alternatives using various LCA program results. CAS, ...