Arm exercise capacity, heart rate recovery, and delta heart rate predict 12-year all-cause mortality and arm exercise–induced ST changes, limiting angina, and an abnormal nuclear imaging result portend coronary revascularization in lower extremity disabled veterans. 展开 ...
Arm exercise capacity, heart rate recovery, and delta heart rate predict 12-year all-cause mortality and arm exercise鈥搃nduced ST changes, limiting angina, and an abnormal nuclear imaging result portend coronary revascularization in lower extremity disabled veterans....
In the nucleus, the altered PHGDH activity restricts NAD+ level and compartmentally repressed NAD+-dependent PARP1 activity for poly(ADP-ribosyl)ation of c-Jun, thereby leading to impaired c-Jun transcriptional activity linked to cell growth inhibition. Physiologically, nuclear PHGDH sustains tumour ...
This editorial is a tutorial on this new approach and is an attempt to show where the approach fits in with conventional analyses and when it may be an oversimplification.关键词:disaster earthquake nuclear accident radiology department tsunami ...
Intravenous dipyridamole comvined with handgrip stress provides a potent stimulus for purposes of diagnostic perfusion imaging. Although planar and single photon emission computed tomography (SPECT) imaging also have played an important role, these techniques are seriously hindered by their inability to ...
Statistics were calculated using two-sided equal variance t-test. ΔCt values were calculated relative to the housekeeping gene RPLP0. *p < 0.05, **p < 0.01, ***p < 0.001. pUTR proximal UTR, dUTR distal UTR, fraction T total, C cytoplasmic, N nuclear. Full size image ...
and myotubes differentiated to 7 days (right).CRYR1 immunocytochemistry with nuclear stain DAPI in C2C12 differentiated into myotubes at 8 days of serum starvation – note these are not organised as in mature myofibres. (Scale bar represents 50 μm). Created inBioRender.com...
The poly(a)-binding protein nuclear 1 suppresses alternative cleavage and polyad- enylation sites. Cell 2012; 149:538-553. 19 Baurle I, Dean C. The timing of developmental transitions in plants. Cell 2006; 125:655-664. 20 Terzi LC, Simpson GG. Regulation of flowering time by RNA ...
Bioenergetic failure caused by impaired utilisation of glucose and fatty acids contributes to organ dysfunction across multiple tissues in critical illness. Ketone bodies may form an alternative substrate source, but the feasibility and safety of inducin
Several lines of evidences implicate the intron-retained transcripts are likely to be less stable than those fully spliced ones38,39,40. IR is also showed to reduce the levels of transcripts through both nuclear sequestration and turnover and nonsense-mediated mRNA decay of intron-retained ...