Ibuprofen, for instance, is known to kill thousands each year, and is believed no less dangerous than Merck’s COX-2 inhibitor NSAID drug Vioxx which caused between88,000-140,000 cases of serious heart diseasein the five years it was on the market (1999-2004). Pine Bark Extract (Pycnogen...
0053 : Naproxen as an alternative to aspirin for platelet inhibition in patients with cardiovascular disease requiring nonsteroidal anti-inflammatory drug?Concomitant prescription of non-steroidal anti-inflammatory drugs (NSAIDs) and low dose aspirin is not recommended due to competitive interaction with ...
Comparative genomics allowed the identification of drug targets against human fungal pathogens Thus, the search for alternative therapies and/or the development of more specific drugs is a challenge that needs to be met. Genomics has created new ... AKR Abadio,ES Kioshima,MM Teixeira,... - 《...
Revisiting Terminalia arjuna - An Ancient Cardiovascular Drug. Terminalia arjuna, commonly known as arjuna, belongs to the family of Combretaceae. Its bark decoction is being used in the Indian subcontinent for anginal... S Dwivedi,D Chopra - 《Journal of Traditional & Complementary Medicine》 ...
Ephedra. This is a herbal product (ma huang) used for weight loss and performance enhancement. It contains ephedrine and pseudoephedrine. Non-herbal forms of these drugs are used as decongestants. Ephedra accounts for 64% of all adverse herbal reactions. We see no reason to use this drug in...
which must be spelled out in order to defend against a possible objection. For some SM therapies, such as aspirin and cancer chemotherapy (Shahvisi2016) there is no firm consensus as to the mechanism. Yet it is important to note that this is a matter of over-determination; the lack of ...
ContextDespite concerns about drug safety, current information on older adults' use of prescription and over-the-counter medications and dietary
A loading dose of 200 mg/kg MgSO4 was given over 20 minutes, followed by a continuous infusion of 20-150 mg/kg/hour to obtain a magnesium blood concentration between 3.5 and 5.5 mmol/l. Mean (SD) duration of treatment was 75.5 (19.8) hours. No other vasodilatory drug was administered...
Drug interactions can occur at the pharmaceutical, pharmacody-namic, or pharmacokinetic level. Herbals and dietary supplements containing St John's Wort (Hypericum perforatum), ginkgo (Ginkgo biloba), kava (Piper methysticum), digitalis (Digitalis purpurea), willow (Salix alba), magnesium, calcium ...
Therefore, new antiaggregatory substances, particularly inhibitors of the P2Y12 receptor, are needed that show reversible binding to the receptor with a fast, strong and long-lasting and direct antiplatelet effect (no pro-drug, i.e., no need for hepatic metabolic activation)...