50% reduction in production culture duration Elimination of centrifugation and depth filtration equipment and operations Healthier culture, which translates to lower HCP and lower process-related impurities Closed system and single-step process Harvested material that is 0.2 µm filtered and ready for p...
DISPOSABLE ALTERNATING TANGENTIAL FLOW FILTRATION UNITSDisclosed herein are robust disposable alternating tangential flow (ATF) housing and diaphragm pump units and associated methods of manufacturing, testing, wetting, and using the same.WARD Travis R....
(s) of a hollow fiber filter should filter element11correspond to a hollow fiber filter. The filter channels collectively correspond to the retentate chamber45of the fluid filtration system L In one direction, the fluid flow proceeds to, and exits from, the exit end43of the filter element11....
tangentialflowATFenergydissipationratefiltrationfluxhighIn this study, we investigated the effects of ATF cell separation on high-density perfusion cultures. We have developed methods to estimate theoretical residence times of cells in the ATF system and discovered that long residence times (above 75 ...
Disposable Alternating Tangential Flow Filtration UnitsDisclosed herein are robust disposable alternating tangential flow (ATF) housing and diaphragm pump units and associated methods of manufacturing, testing, wetting, and using the same.TRAVIS R. WARD...
Disposable alternating tangential flow filtration unitsDisclosed herein are robust disposable alternating tangential flow (ATF) housing and diaphragm pump units and associated methods of manufacturing, testing, wetting, and using the same.Travis R. Ward...
In the present study, we established an automated perfusion process for production of a DIP, called DI244, using an alternating tangential flow filtration (ATF) system for cell retention. Viable cell concentrations and DIP titers more than 10-times higher than for a previously reported batch ...
DISPOSABLE ALTERNATING TANGENTIAL FLOW FILTRATION UNITSDisclosed herein are robust disposable alternating tangential flow (ATF) housing and diaphragm pump units and associated methods of manufacturing, testing, wetting, and using the same.WARD Travis R....
Disclosed herein are robust disposable alternating tangential flow (ATF) housing and diaphragm pump units and associated methods of manufacturing, testing, wetting, and using the same.ワード,トラビスアールパール,スティーブンアールマローン,アダム...
A micro alternating tangential flow (microATF) perfusion filter includes a hollow cylinder having a proximal end and a distal end. The proximal end is connected in series to a permeate chamber, followed by a retentate chamber. The proximal end either (i) terminates in or at the permeate ...