HGSOC is the leading cause of gynecologic cancer death in the United States (25) for which most women will present with advanced-stage disease and ultimately die of their disease within five years (26). Thus, ne
Deregulation of phospho-dephosphorylation processes often leads to cell abnormalities or even cell death, and is at the basis of many human diseases23. The need for fine regulation of Ppz1 function was first deduced from the observation that expression of the phosphatase from an episomal ...
EGF not only prevented cell death in EGFR-expressing cells but mimicked the proliferative effect of IL-3. In EMC-expressing cells, EGF activation of the Mer signal resulted in a nearly stable cell number over 96 h (Fig. 4 and TableI). In contrast a 32D cell stably expressing a kinase...
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