Significant positive correlations between ALT/AST and NAFLD risk were found across all models. In addition, the subgroup analysis by gender, age, and BMI suggested that ALT/AST showed a positive correlation with NAFLD. The ALT/AST ratio was positively correlated with the ...
When the AST:ALT ratio rises above 1, fibrosis can be suspected, indicating that all is not normal.[viii] Non-alcoholic fatty liver disease (NAFLD) without fibrosis or cirrhosis may be associated with an AST:ALT ratio below 1. The AST:ALT ratio is incorporated into a comprehensive NAFLD ...
The aspartat aminotransferase (AST)/alanin aminotransferase (ALT) (De-Ritis) ratio (AAR) is an easily applicable blood test. An elevated AAR on the one hand has been associated with an increase in nonalcoholic fatty liver disease (NAFLD). NAFLD on the other hand is associated with an incre...
主要指标ALT和次要指标AST、TBil采用平均差(mean difference,MD)和95%可信区间(confidence interval,CI)表示,次要指标总有效率选用比值比(odds ratio,OR)表示。根据异质性的检验结果选择随机效应或固定效应模型估计总的效应。Q检验和I2...
NAFLDfibrosisscores (NFS) = -1.675 + 0.037 × age (year) + 0.094 ×BMI(kg/m2) + 1.13 × IFG/diabetes (yes = 1, no = 2) + 0.99 ×AST/ALT ratio− 0.013 × platelets (109/L) − 0.66 × albumin (g/dL), which is recommended by the EASL-EASD-EASO Clinical Practice Guidelines...
Aside from FibroScan, various alternative non-invasive methods have been developed for the assessment of liver fibrosis in NAFLD during the past decade, such as aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio, fibrosis-4 (FIB-4) score, and AST to platelet ratio index (APRI) [...
认为前三者伴NAFLD和ALT升高者会增加相关死亡率. 有学者甚至将ALT、AST及AST/ALT比值的常规健康检查作为预测CVD死亡标记的简单而重要的指标之一[13,56]. 这些研究结果表明, 升高的AST/ALT比值可能更多地体现系统紊乱不单纯局限于肝损伤[57], 亦与冠状动脉钙化的发生风险相关[58]. Kotronen等[59]还发现, 与同样...
Results: (1) The ratio of NAFLD in Eastern China was 15%. It was higher in males than in females (P<0.01). (2) Compared with control group, the alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum total triglycerides (TG), serum total cholesterol (TC), low-density ...
Signifi- cance of ALT / AST ratio for specifying subjects with metabolic syn- drome in its silent stage[J]. Diabetes & Metabolic Syndrome: Clini- cal Research & Reviews,2009,3( 1) : 3 - 6Hideki Ohgo,Hirokazu Yokoyama,Hiroshi Hirose, et.al.Significance of ALT/AST ratio for specifying ...
The aspartat aminotransferase (AST)/alanin aminotransferase (ALT) (De-Ritis) ratio (AAR) is an easily applicable blood test. An elevated AAR on the one hand has been associated with an increase in nonalcoholic fatty liver disease (NAFLD). NAFLD on the other hand is associated with an ...