Aoyama N,Katayama Y,Kawamata T,et a1. Effects of antioxidant,OPC-14117,on secondarycellulardamage and behavioral deficits following cortical contusion in the rat[J].Brain Res,2002,934(2):117—124. Abe K, Morita S, Kikuchi T,et a1.Protective effect of a novel free radical scavenger,()PC...
ALS can also affect the brain and cause frontal-temporal dementia. Death usually follows on average in three to five years after the onset. In Central Finland Central Hospital a multidisciplinary team is involved in ALS rehabilitation. An occupational therapist is a member of this team. An ALS-...
Amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s Disease, is a progressive disease of the nervous system that affects the nerve cells in the brain and spinal cord and their ability to control the muscles. ALS often begins with either muscle twitching and muscle weakness in the...
Its compounds may interact with ALS medications or cause other side effects. Some products may be more effective for certain symptoms than others, so getting the appropriate guidance is important.Pain reliefPeople with ALS commonly experience pain that can stem from extra strain on their muscles ...
traumatic brain injuries (TBIs), which happen when the brain is damaged by external impacts such as a fall or a car accident, can accelerate the onset and progression of amyotrophic lateral sclerosis (ALS) associated with mutations in the SOD1 gene, a new mouse study suggests. The effects ...
Many have other physiological effects on neurons such as ind... SC Apfel - 《Brain Pathology》 被引量: 270发表: 1999年 Neurotrophic factors and their receptors in human sensory neuropathies. Neurotrophic factors may play key roles in pathophysiological mechanisms of human neuropathies. Nerve growth ...
Beyond the first symptoms, ALS continues to progress. People typically have trouble lifting things, or using their hands for tasks. Their balance and gait will change, with increased risks of trips and falls. Work, school, home, and hobbies become a challenge. Over time, the effects of ALS...
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effects on DPR content45,46irrespective of its action on the UPR. This is highly relevant to the disturbances observed in deep layer corticospinal neurons contributing to motor dysfunction in ALS/FTD and supports the susceptibility of the primary motor cortex to such effects50. Whether the onset ...
A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine: effects on CSF glutamate, aspartate, branched-chain amino acid... Objectives A study was conducted to examine the effect of lamotrigine (LTG) in amyotrophic lateral sclerosis (ALS). Material and methods Patien...