参考 【1】:Uccelli A,Milanese M,Principato MC,et al.Intravenous mesen- chymal stem cells improve survival and motor function in experi- mental amyotrophic lateral sclerosis [ J ].Mol Med, 2012, 18: 【2】:Kim HY,Kim H,Oh KW,et al.Biological markers of mesenchy- mal stromal cells as p...
Stem cells have captured the imagination of people with ALS. The potential promise of neuronal replacement and regeneration, as well as replacement and regeneration of other neural tissues, through stem cell therapies, has become a source of great hope and expectation. While just more than a ...
告诉大家一个好消息,Dr. Clive Svendsen近日将来北京参加学术会议,他将分享更多有关再生医学与干细胞的最新前沿进展。Dr. Svendsen还将带来学术报告《干细胞治疗是永葆青春的神药还是幻想?》(“Stem cells and the fountain of youth: Fact or Fiction?”),永葆青春究竟只存在于科幻小说中,还是可以变为现实?Dr. S...
Eggan K. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science. 2008 Aug 29;321(5893):1218-21. doi: 10.1126/science.1158799. Epub 2008 Jul 31. PMID: 18669821.
Injections of stem cells that are induced to secrete neurotrophic factors in patients with amyotrophic lateral sclerosis (ALS) are safe, well tolerated, and possibly clinically beneficial, results of a small open-label study suggest. Although the results have to be confirmed with a clinical trial,...
(ANSA) - Rome, May 28 - Tests by Italian doctors in which human neural stem cells were injected into sufferers of amyotrophic lateral sclerosis (ALS) show the procedure is safe and effective, according to a paper published in the Stem Cells Translational Medicine journal. As a result the ...
Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials. OBJECTIVE: To test the safety of spinal cord transplantation of human stem cells in patients with amyotrophic lateral sclerosis (ALS) with escalating doses and expansion of the trial to multiple ...
Directed Differentiation of Human Induced Pluripotent Stem Cells to Heart Valve Cells Circulation; IF: 37.800; DOI: 10.1161/CIRCULATIONAHA.123.065143 内容概要: ① 当前心脏瓣膜疾病研究面临的主要挑战是缺乏高质量、同质性好的功能性心脏瓣膜细胞。为了克服这一难题,研究者们转向人类诱导多能干细胞(hiPSCs)作为潜...
Carlo Agostini.Stem cell therapy for chronic lung diseases: Hope and reality,2010Agostini C. Stem cell therapy for chronic lung diseases: hope and reality... Carlo,Agostini - 《Respir Med》 被引量: 61发表: 2010年 Homologous Recombination in Human Embryonic Stem Cells: A Tool for Advancing Cel...
There is no way to prevent or cure ALS, but it is possible to slow thedisease progressionwith appropriate treatment. Many researchers and clinical trials are working on trying to find treatments for ALS. Therapies on the horizon involve stem cells that could help to protect remaining motor neuro...