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8 0-0.4 0.2 0.2 4.8 × 1010 EXAMPLE 5 Drug Mass Density and Rate of Drug Aerosol Formation of Midazolam Aerosol [0091] A solution of 16.7 mg midazolam in 200 μL dichloromethane was spread out in a thin layer on the central portion of a 4 cm×9 cm sheet of aluminum foil...
We developed a serum metabolomic method by gas chromatography‐mass spectrometry (GC‐MS) to evaluate the effect of alprazolam in rats. The GC‐MS with HP‐5MS (0.25 µm × 30 m × 0.25 mm), mass was conducted in EI mode with electron energy of 70 eV, full‐...
patients′ adherence to treatment, their general health status, the presence of adverse effects, and the perception of health status were evaluated. The latter was evaluated by means of a Health Scale with the following five response options: 0 = a perception of poor health status; 1 = fair...
A sample of n=55/182 patients will be considered enough to detect variables higher than 25% (pretreatment vs post-treatment or significant correlations) with a 1- power of 0–80. t Test and/or non-parametric test, and Pearson's test for correlation analysis will be determined. This study...
Dosage was adjustable from 0.5 mg alprazolam, 25 mg imipramine or two capsules placebo b.i.d. to 4.5 mg alprazolam, 225 mg imipramine or three capsules placebo t.i.d. Both active drugs were more effective than placebo according to all the rating scales used. Alprazolam and imipramine did ...
Group DEX received intranasal dexmedetomidine 1 mcg/kg (ideal body weight) while other group (AZ) received oral alprazolam 0.5 mg. Sedation scale, heart rate and the mean arterial pressure was assessed in both the groups at 0 hour, 45 minutes, during laryngoscopy and tracheal intubation. ...