此外,还有名为AlphaFold-linker的方法,其类似于上述策略1;以及利用colabfold的名为AlphaFold-Gap的方法类似上述策略3。此均不详述。 正是在AlphaFold2开源后关于复合体结构预测的“二创”工作层出不穷的背景下,DeepMind于2021年10月4日在bioRxiv发布了AlphaFold-Multimer(简称AFM)的预印论文(而后在2022年3月10日更新...
1.5万 2 4:17 App 使用Google CoLab & AlphaFold2 预测蛋白三维结构 1081 1 45:14 App 【Insight Time】浅谈 AlphaFold 与蛋白质结构预测 1646 -- 4:06:16 App 基于深度学习的蛋白质结构预测讲座——许锦波 978 1 1:33:50 App mRNA药物的结构表征和特性鉴定---LNP载体药物的质量表征与配方优化 946...
两条链之间通过Pair bias和Outer product mean两个单元还能进行信息的融合。Evoformer通过双链的模式，让...
You can use a slightly simplified version of AlphaFold with this Colab notebook or community-supported versions (see below).First time setupThe following steps are required in order to run AlphaFold:Install Docker. Install NVIDIA Container Toolkit for GPU support. Setup running Docker as a non-...
Benchmarking ColabFold in CASP15. CASP15 abstracts https://predictioncenter.org/casp15/doc/CASP15_ Abstracts.pdf, 50–51 (2022). 51. Elofsson, A. et al. Elofsson group using AlphaFold2 and MolPC in CASP15. CASP15 abstracts https://predictioncenter.org/casp15/doc/CASP15_Abstracts...
ColabFold database: ~1.7T Integrated Microbial Genomes (IMG): ~1.5T Metaclust: ~114G STRING: ~129G pdb_complex: ~38G pdb_sort90: ~48G Uniclust30: ~87G Important parameter values in db_option # AlphaFold2 parameters monomer_num_ensemble = 1 monomer_num_recycle = 3 num_monomer_prediction...
ColabFold used a flexible linker solution which didn't provide the same accuracy but also never displayed these clashes. Some proteins work very well and it's been great seeing these models. But whenever a protein has some region with low confidence it quickly becomes a tangled mess. I've ...
在对 30 道奥数几何题的基准测试中，AlphaGeometry 在标准奥数时限内解决了 25 道。相比之下，之前最...