( 1987b ) Alpha 2-antiplasmin Enschede: alanine insertion and abolition of plasmin inhibitory activity . Science , 238 , 209 – 211 .Holmes WE, Lijnen HR, Nelles L, Kluft C, Nieuwenhuis HK, Rijken DC, Collen D. Alpha 2-antiplasmin Enschede: alanine insertion and abolition of plasmin ...
Alpha-antiplasmin-deficiency is a rare coagulation disorder which allows unrestrained fibrinolytic activity. Individuals with this condition may receive therapeutic A2AP prior to surgery to prevent postoperative hemorrhaging. Purity: >=95% by SDS-PAGE Specific Activity: >= 5.0 IU/mg Prepared from ...
and placenta also express its mRNA at a moderate level. The tissue expression pattern indicates that it is a key regulator of plasmin mediated proteolysis in these tissues. Alpha-Antiplasmin-deficiency is a rare coagulation disorder which allows unrestrained fibrinolytic activity. Individuals with this...
Objective Systemic sclerosis (SSc) is characterized by fibrosis of the skin and visceral organs. Patients with SSc have enhanced plasma levels of the plasmin–α2-antiplasmin (α2AP) complex, and we re...
Alpha-2 Antiplasmin (A2AP)的详细介绍 Product NameAlpha-2 Antiplasmin SourceHuman Plasma Catalogue Number107-50 Purity>95% (SDS-PAGE) FormLyophilized ProteinReported in mg/vial (A280, E0.1%=0.7) Specific Activity>5 IU/mg protein FormLyophilized from 20 mM Bis-Tris, pH 6.4, with 200 mM Na...
Plasmin associated with the spirochete was not inhibited by alpha2-antiplasmin. These results suggest that PAI-1, PAI-2 and alpha2 antiplasmin would not be efficient regulators of fibrinolytic protease activity on the Borrelial surface and would not pose a barrier to utilization of these enzymes...
Novel proteins derived from human alpha2-plasmin i 优质文献 相似文献 参考文献 引证文献NOVEL PROTEINS DERIVED FROM HUMAN ALPHA2-PLASMIN INHIBITOR ORPROTEINS SIMILAR THERETO PURPOSE:To obtain a protein having blood coagulation preventing activity and usable for the prevention, treatment or remedy for card...
It was further found that comparison of purified 伪2-antiplasmin and that in plasma was prevented by the deviation. The difference between calculated and measured plasmin activity could not be attributed to instability of plasmin. It was established that the observations (1) were specific for high...
The serpin, alpha(2)-antiplasmin (alpha(2)AP), has an extended C-terminus relative to other inhibitors. This 51-residue region contains an RGD sequence; such sequences constitute a key recognition sequence for cell adhesion, mediated through integrins. In the present study, this sequence was ...
PREPARATION OF VIRALLY INACTIVATED BIOLOGICAL FLUIDS HAVING HIGH ALPHA-2-ANTIPLASMIN ACTIVITYThe invention relates to the use of polyoxyethylene (4-5) p-t-octyl phenol (t-Oct-C6H4- (OCH2CH2) x0H, x= ~5) or polyoxyethylene (20) sorbitan monooleate in solvent/detergent viral inactivation of...