Journals & Books Help Search My accountSign inAlpha Blocker In subject area: Agricultural and Biological Sciences About this pageAdd to MendeleySet alert On this page On this page Chapters and Articles You might find these chapters and articles relevant to this topic....
(ERα) andestrogen receptor beta(ERβ). Though the two receptors are only 16% similar in theiramino acid sequence, they both act as transcription factors and each consist of three functional domains: the NH2-terminal domain (NTD), theDNA bindingdomain (DBD), and the COOH-terminalligand ...
Although 3%–5% of estrogen receptors (ER-alpha/beta) localize to the endothelial plasmalemma, these receptors are responsible for the nongenomic vasodilator responses. Estradiol induces endothelial NO synthase (eNOS) activation to increase NO production; however, it is unknown if eNOS regulation is ...
Define alpha blocker. alpha blocker synonyms, alpha blocker pronunciation, alpha blocker translation, English dictionary definition of alpha blocker. n. any of various substances that interfere with the action of the alpha-receptors. al′pha-block`ing, a
to distinguish the first in a series of isomers, or to indicate the position of substituent atoms or groups; also used to distinguish types of radioactive decay, brain waves or rhythms, adrenergic receptors, and secretory cells that stain with acid dyes, such as the alpha cells of the pancre...
Dysregulation of estrogen receptor alpha (ERα) has been linked with increased metabolic and cardiovascular disease risk. Here, we generate and characterize cardiomyocyte-specific ERα knockout (ERαHKO) mice to assess the role of ERα in the heart. The
Concomitant blockade of α 1 -/α 2 -adrenoreceptors by phentolamine (0.5 mg/ml/min infused iv from 60 to +30 min) abolished the GHRH-induced GH rise (645.5± 106.0 versus 189.0±58.8 μg/l/h; P<0.01). Finally, the GHRH-stimulated release was blunted by β 2 -adrenergic stimulation...
Glycosylation of the single carbohydrate chain of the beta subunit preferentially affects metabolic clearance of the hormone versus alpha subunit glycosylation, whereas glycosylation of N52 appears to be more important than that of N78 in the alpha subunit.43,46 These studies emphasize the importance ...
Ligands for these receptors have been identified and belong to at least two cytokine superfamilies. Gruss and Dower, supra. Tumor necrosis factor (a mixture of TNF-alpha and TNF-beta) was originally discovered as a result of its anti-tumor activity, however, now it is recognized as a ...
In general, receptors can be membrane bound, cytosolic or nuclear ; monomeric (e. g., thyroid stimulating hormone receptor, beta- adrenergic receptor) or multimeric (e. g., PDGF receptor, growth hormone receptor, IL-3 receptor, GM-CSF receptor, G-CSF receptor, erythropoietin receptor and IL...