ThalassemiaFetal HemoglobinGlobinsHemoglobin, SickleChromosome MappingHaplotypesHomozygoteThe interaction of α thalassemia with Hb SS entails complicated trade-offs among cellular variables, hematologic and vasoocclusive severity, and life expectancy. The complexity of these considerations has been further ...
Thus, individuals who inherit alpha-thalassemia and sickle cell anemia may represent a subgroup of patients with a longer life expectancy. 展开 DOI: 10.1002/ajh.2830140412 被引量: 99 年份: 1983 收藏 引用 批量引用 报错 分享 全部来源 求助全文 ResearchGate EBSCO 相似文献 参考文献 引证文献...
The thalassemias are a group of inherited hematologic disorders caused by defects in the synthesis of one or more of the hemoglobin chains. Alpha tha..
Our son was diagnosed with ATR-X (alpha thalassemia intellectual disability x-linked syndrome) in June 2016. My husband and I received the diagnosis via a phone call from our geneticist while sitting in a grocery store parking lot in our car. That phone call changed our lives but we’d kn...
Beta-Thalassemia Major (Cooley’s Anemia): Characterized by two defective genes; almost no function of either gene, leading to no synthesis of beta-globin. These individuals have a severe form of disease requiring lifelong transfusion and may have shortened lifespans. ...
Alpha-thalassemia is related to prolonged survival in sickle cell anemia. Blood. 1983;62(2):286-290.Mears, J. G., H. M. Lachman, D. Labie, and R. L. Nagel. 1983. Alpha thalassemia is related to prolonged survival in sickle cell anemia. Blood. 62:286-290....
Persons with the thalassemia trait have a normal life expectancy. Persons with beta thalassemia major often die from cardiac complications of iron overload by 30 years of age.Herbert L MuncieJames CampbellAmerican Family PhysicianCampbell JS. Alpha and beta thalassemia. Am Fam Physician. 2009 Aug ...