在牛市期间,beta系数的分散性要低得多,因此,低波动性股票的表现不会太差,即使有的话也不行,而在危机期间,投资者寻求或保持低波动性股票,贝塔的分散性会增加。 因此,长期来看,波动性较低的资产和投资组合的表现更好。 如何衡量波动率和规模 用于识别低波动性股票的指标涵盖范围很广,一边实现了波动率(标准差),...
This section provides a quick introduction of protein secondary structures, alpha helix and beta sheet. Both structures are stabilized by hydrogen bonds between oxygen atoms and hydrogen atoms of two amino acid residues lined up side by side.
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However, under the circumstances we have discussed above, the protein can undergo a conformational transition to a beta-sheet-rich structure that polymerizes to form toxic oligomers and amyloid plaques. Evidence from autopsy studies of patients with advanced PD implies alpha-synuclein is an aberrantly...
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Particularly, Al(III) is capable of inducing β-sheet formation and subsequent aggregation of Aβ40 (Zhang et al., 2019). Similar effect was observed for Aβ42 with Al(III) and Fe(II)/Fe(III) being more active promoters of Aβ42 aggregation than Cu(II) and Zn(II) (House et al....
Tau aggregation is driven by a transition from random coil to beta sheet structure. Biochim. Biophys. Acta (BBA)-Mol. Basis Dis. 1739, 158–166 (2005). Article CAS Google Scholar Seidler, P. M. et al. Structure-based inhibitors of tau aggregation. Nat. Chem. 10, 170–176 (2018)....
by Seeking Beta To Your Alpha Well written article. You have solid reasoning and describe the reality clearly. I also own puts on Yelp, and I will continue to buy them. Anyone who understands business/competition OR can read a balance sheet should be salivating at the ridiculous multiple of...
In buffers containing 10% acetonitrile, 104H1 was converted into the beta-sheet form by addition of as little as 1% H1. In addition, A beta 11-25 and A beta 25-35 peptides with similar physical properties to H1 were incapable of converting H2 into the beta-sheet form. How well these...
The A11 antibody, for example, binds the beta-sheet edge in pre-fibrillar oligomers suggesting this is a common motif in pathogenic oligomers [73]. A shortcoming of the broad specificity of A11 is that it results in the detection of non-pathogenic proteins that contain the beta-sheet edge ...