We have applied globin synthesis and free alpha-chain pool studies of peripheral blood to characterize hematologic disorders where alpha- or beta-thalassemia was present in combination with HbS or HbC. In 60 non-thalassemic controls, the beta/alpha specific activity ratio was 1.01 +/- 0.06 (SD)...
(redirected fromAlpha-thalassemia) Thesaurus Medical Encyclopedia Related to Alpha-thalassemia:Beta-thalassemia,hemoglobin H disease thal·as·se·mi·a (thăl′ə-sē′mē-ə) n. An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of ...
The meaning of ALPHA-THALASSEMIA is thalassemia in which the hemoglobin chains designated alpha are affected.
The Frequency and Importance of Common [alpha]-globin Gene Deletions Among [beta]-Thalassemia Carriers in an Iranian Population Gwendolyn Muse Charles Alpha Kappa Alpha New Orleans, La. Spring 2007 Ebony Fashion Fair chairpersons The SDF alpha depends on the model for the SDF, and theoretically ...
The first, known as alpha-thalassemia-2 trait, is characterized by the absence of 1 of 4 alpha globin genes. While each normal human chromosome has only 1 copy of the beta globin gene, there are 2 copies of the alpha globin genes. Only 1 functioning copy of each alpha globin gene is ...
Combination of a triple alpha-globin gene with beta-thalassemia in a gypsy family: importance of the genetic testing in the diagnosis and search for a dono... The simultaneous presence of a heterozygous β-thalassemia with α-gene triplication may cause anything from a thalassemia trait to ...
Alpha chain inclusions in E/beta thalassemiaatherosclerosismatricellular proteinstransgenic micevascular inflammationAm J Hematol. 2008 Nov;83(11):871. doi: 10.1002/ajh.21223. Case Reportsdoi:10.1002/ajh.21223Barbara J. BainDepartment of Haematology, St. Mary's Hospital Campus of Imperial College ...
Alpha is derived from a in the formula Ri = a + bRm, which measures the return on a security (Ri) for a given return on the market (Rm) where b is beta. b. The return on an investment portfolio that can be attributed to the skill of the portfolio's manager rather than the ...
ThalassemiaDNA Restriction EnzymesGlobinsChromosome MappingGenotypeErythrocyte IndicesHemoglobinsHeterozygoteThe alpha globin genotypes of 55 beta thalassaemia heterozygotes have been determined by restriction endonuclease analysis to identify those with interacting alpha thalassaemia genes. A comparison of the ...
5.1Alpha-thalassemia Thalassemiais an inherited disorder of defective alpha-globulin or beta-globulin ofhemoglobin Asubunits. Thealpha-thalassemiagene is located onchromosome 16and four alleles control the synthesis of α-globulin (α1−/− and α2−/−) and the number of allele deletions is...