Depending on the circumstances, a doctor may prescribe one or more of these tests to determine whether a person has an inherited condition affecting the alpha-1 antitrypsin protein. Multiple tests may be prescribed at the same time, or they can be done in a sequence of initial testing with f...
Alpha‐1‐antitrypsinZ variantChronic obstructive pulmonary diseaseLiver diseaseLaboratory testingAlpha(1)-antitrypsin deficiency is characterized by a pathologic reduction of the serum concentration of alpha(1)-antitrypsin, the most important antiprotease in . It is one of the most common in Caucasians...
Gene Symbol Alpha 1-Antitrypsin Gene ID (NCBI) 5265 RRID AB_10641185 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification UNIPROT ID P01009 Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year...
Alpha-1 antitrypsin(抗胰蛋白酶) deficiency is a genetic disorder(遗传病) in which a protein called alpha-1 antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺...
Alpha-1 antitrypsin deficiency (A1ATD) in one of the most common genetic causes of liver disease in children. We aimed to analyze the clinical characteristics and outcomes of patients with A1ATD.This study included patients with A1ATD from five pediatric hepatology units. Demographics, clinical fin...
Inherited deficiency of alpha-1-antitrypsin is one of the best know abnormalities affecting the lungs. DNA sequence of the responsible gene has been identified, and the gene has been cloned. Genetically engineered alpha-1-antitrypsin has been synthesised and treatment with synthetic protein has been...
Background: Alpha-1 antitrypsin deficiency (AATD) is a genetic condition characterized by low serum levels of the protein alpha-1 antitrypsin. Because there are no unique clinical symptoms that point to a definitive diagnosis of AATD, laboratory testing is crucial to differentiate this disease from...
Diagnosis of alpha-1 antitrypsin deficiency often begins with a chest X-ray or Chest CTto look for hyperinflated(过度膨胀)lungs or evidence of damaged lung tissue. 一般诊断的话肺就看胸片或者CT,或者找到一些肺损伤的证据 In addition, pulmonary function testing can be used to measure how quickly ...
Alpha-1-antitrypsin deficiency and juvenile liver disease Ultrastructural observations compared with light microscopy and routine liver tests Sixteen children (aged between 1 month and 20 years) with 伪-1-antitrypsin deficiency (PiZ) were investigated by liver biopsy on one or more occasions. Eig......
Storage ConditionsStore at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.20ul sizes contain 0.1% BSA. Background Information SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT), which is a serine protease inhibitor whose targets include...