Alpha-gal allergy is a reaction where the immunoglobulin E antibody elicits a response to galactosealpha-1,3-galactose (alpha-gal) which is a mammalian oligosaccharide epitope found in nonprimate mammalian. After being exposed to a tick bite, particularly the Lone Star tick (Amblyomma americanum)...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Alphagan Brimonidine Ophthalmology An alpha-2 agonist for treating open-angle glaucoma. See Open angle glaucoma. McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc. ...
Another strategy is introducing the human α-galactosidase (GLA) gene into pig genome. The GLA enzyme can remove the α-D-galactose from the Gal epitope on the pig cell surfaces, but not completely [55]. The expression of EndoGalC, HT, and GLA are all aimed to inhibit HAR, bu...
The presence of alpha-Gal-containing epitopes was confirmed by ELISA and immunoblotting following removal of terminal alpha-Gal epitopes by alpha-galactosidase treatment. These results suggest for the first known time that bites from the A. sculptum tick may be associated with the unknown etiology ...
An alpha-galactosidase (alpha-D-galactoside galactohydrolase [EC 3.2.1.22]) was purified to homogeneity from the culture filtrate of Aspergillus niger. The enzyme had an apparent molecular weight of 45,000 and was a glycoprotein. Radioactive enzyme was prepared by growing cells in [14C]fructose ...
Biochemical and Phylogenetic Analyses of a Cold-Active β-Galactosidase from the Lactic Acid Bacterium Carnobacterium piscicola BA We are investigating glycosyl hydrolases from new psychrophilic isolates to examine the adaptations of enzymes to low temperatures. A beta-galactosidase fr......
The increase in cell number is assessed with an appropriate detectable marker gene such as beta-galactosidase, if desired, in a high throughput or ultra high throughput assay format. Receptors that activate the G protein, Gq, elicit the proliferative response. Alpha-adrenergic receptors, which ...
In yet other embodiments, the fusion protein comprises any of the aforesaid antigenic peptides and beta-galactosidase. In still other embodiments the fusion protein comprises any of the aforesaid antigenic peptides and glutathione S-transferase. In yet other embodiments, the fusion protein comprises ...
Total tryptase levels (alpha-tryptases plus beta-tryptases, primarily alpha-protryptase at baseline) were measured on the UniCAP system (Pharmacia-Upjohn, Peapack, NJ) with the use of mAbs B12 for capture and beta-galactosidase-G4 for detection. Statistical analysis Comparisons for statistical ...
11.Bergeron C, Pagé N, Joubert P, Barbeau B, Hamid Q, Chakir J. Regulation of procollagen I (alpha1) by interleukin-4 in human bronchial fibroblasts: a possible role in airway remodelling in asthma.Clin Exp Allergy. 2003;33:1389-1397.[PubMed][DOI][Cited in This Article:2][Cited by...