Pregnancy Third TrimesterMaternal-Fetal ExchangeAnalysisAssay of alpha-1 fetoprotein (AFP) by counterimmunoelectrophoresis (CIEP) is proposed as a simple rapid screening test for fetal distress or death. A study of 298 maternal sera prior to term showed that 291 had less than 250 ng. AFP. ...
Alpha-fetoprotein screening in large scale use implies certain practical consequences in obstetric practice as e.g. performance of a number of control assays in maternal serum (MS-AFP), amniocentesis and ultrasonic examinations. Considerable regional differences were observed in the incidences of ...
What is Alpha-Fetoprotein (AFP)? Alpha-fetoprotein (AFP) is a major carcinoembryonic proteinproduced by the liver and the yolk sac during fetallife. Since blood AFP levelsare elevatedin more than 70% of hepatocellular carcinoma patients, it is considered a representative marker for this disease. ...
Immunomodulatory impact of α-fetoprotein Highlights Cord blood-derived alpha-fetoprotein (AFP) has an incompletely understood role in pregnancy, as well as in autoimmune diseases.AFPis currently being investigated as a potential therapeutic for multiple autoimmune diseases. These diverse biological roles ...
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. It is a common screening test during pregnancy while hight level of
Alpha-fetoprotein (AFP) has been recognized as a key regulator of cell proliferation in hepatocellular carcinoma (HCC). However, whether AFP functions in cancer cell autophagy remains unknown. This study investigated the effects of AFP on autophagy in HCC cells. The role of AFP was studied in ...
Maternal plasma alpha-fetoprotein in normal and complicated pregnancies. Br. J. Obstet. Gynaecol. 83, 24–32 (1976). 41. Roop, A. P., Boughman, J. A. & Blitzer, M. G. Study of the relationship between elevated maternal serum alpha-fetoprotein and adverse pregnancy outcome. MD Med. ...
maternal serum alpha fetoprotein (MSAFP)triple testpregnancy complicationSubchorionic hematoma might be associated with poor pregnancy outcome. Two intra cytoplasmic sperm injection pregnancies complicated with subchorionic hematoma were found to have elevated mid-trimester maternal serum alpha-fetoprotein levels...
ObjectiveTo determine whether a combination of elevated maternal serum alpha-fetoprotein (MSAFP) and low unconjugated estriol (E3) concentration identifies pregnancies at particularly high risk for fetal abnormality or poor outcome.MethodsPregnancy outcomes were reviewed for women with elevated MSAFP (2.0 ...
1990. The effect of smoking in pregnancy on maternal serum alpha-fetoprotein, human chorionic gonadotro- phin, progesterone and dehydroepiandrosterone sulphate levels. Br J Obstet Gynecol 97: 272±276.Cuckle HS, Wald NJ, Densem J, Royston P, Knight G, Haddow J, Palomaki G, Canick J. ...