Wald, N., Barker, S., Peto, R., et al., 1976, Maternal serum alpha-fetoprotein and previous neural tube defects, Br. J. Obstet. Gynaecol . 83 :213.Wald, N. , Barker, S. , Peto, R. , Brock, D. J. H. , and Bonnar, J. ( 1976 ): Maternal serum alphafetoprotein and ...
Maternal alpha-fetoprotein (AFP) or expanded alpha-fetoprotein testing, which includesestrioland HCG to screen forneural tube defects, Down syndrome, and other chromosome abnormalities. False-positive results are not uncommon. View chapter Book
Alpha-fetoprotein (AFP) is a major mammalian embryo-specific and tumor-associated protein that is also present in small quantities in adults at normal conditions. Discovery of the phenomenon of AFP biosynthesis in carcinogenesis by G. Abelev and Yu. Tatarinov 50 years ago, in 1963, provoked in...
(1990) First trimester maternal serum in alpha-fetoprotein and human chorionic gonadotrophin screening for chromosome defects. Fetal Diag. Ther. 7, 123-131.Milunsky, A. , Wands, J. , Brambati, B. , Bonacchi, L. , Currie, K. ( 1988 ). First trimester maternal serum alpha-fetoprotein ...
Alpha-fetoprotein(AFP) is synthesized in the fetal liver and is excreted by the fetal kidneys. It also crosses theplacentaand appears in the maternal circulation by 12 weeks’ gestation.Maternal plasmalevels of AFP are elevated when fetuses haveneural tube defects,abdominal walldefects, oratresiaof...
( 1988 ). First-trimester maternal serum alpha-fetoprotein screening for chromosome defects , Am. J. Obstet. Gynecol. , 159 , 1209 – 1213 .Milunsky, A., Wands, J.R., Bellet, D. (1984). First trimester maternal serum alpha-fetoprotein screening, Pediatr. Res., 19, 328A....
Maternal serum-alpha-fetoprotein (A.F.P.) levels were compared throughout pregnancy in women bearing fetuses with severe neural-tube defects and in control women. From the second trimester onwards, the former group had higher levels than the controls, but the difference was not always clear-cut...
We measured alpha2-macroglobulin concentrations in serum obtained at the time of maternal serum alpha-fetoprotein testing in a sample of 549 patients enriched for IUGR (14%), PTD (24%), and cigarette smoking (16%). Subjects were selected from local private care settings. Mean serum alpha2-...
Summary: Serum α-fetoprotein (AFP) levels were monitored in 32 normal babies consecutively from 2 to 3 days, 2 wk, and 2 and 4 months after birth. In addition, serum AFP concentration was also measured in 116 random specimens from infants with normal li
alpha-fetoprotein (ˌælfəˌfiːtəʊˈprəʊtiːn) n (Biochemistry) a protein that forms in the liver of the human fetus. Excessive quantities in the amniotic fluid and maternal blood may indicate spina bifida in the fetus; low levels may point to Down's syndrome. Abb...