Serum α-fetoprotein levels were determined in patients (268) with liver disease. Markedly elevated concentrations (>100 μg/l) were found in twelve patients with malignant tumours and two with cirrhosis. Molecular variants of α-fetoprotein were distinguished by lectin affinity chromatography of ...
Alpha-fetoprotein (AFP) is a major carcinoembryonic proteinproduced by the liver and the yolk sac during fetallife. Since blood AFP levelsare elevatedin more than 70% of hepatocellular carcinoma patients, it is considered a representative marker for this disease. AFP assay is helpful as an adjunc...
positive of serum alpha-fetoprotein at various levels in the diagnosis of hepatocellular carcinoma, using 54 patients with histologically proven hepatocellular carcinoma and 200 patients with chronic liver disease (40 patients with chronic active hepatitis and 160 patients with cirrhosis) as nontumor ...
Dose per infusion 1.021 0.742–1.407 0.896 Concurrent chemotherapy 3.378 0.682–16.746 0.136 lnAFP- natural logarithmic conversion of serum alpha-fetoprotein, Boldface indicates statistical significance. The median overall survival of the entire cohort was 15.2 months. Increased pretreatment AFP was associat...
摘要: fetoprotein 关键词: Humans Neoplasms Liver Diseases Liver Cirrhosis Pregnancy Complications Fetal Diseases Abnormalities, Multiple Fetal Proteins alpha-Fetoproteins Hepatitis B Antigens DOI: 10.1111/j.1365-3083.1978.tb03870.x 被引量: 32
The Fucosylation Index of Alpha-Fetoprotein and Its Usefulness in the Early Diagnosis of Hepatocellular Carcinoma YUTAKA AOYAGI, MD,' YASUFUMI SUZUKI, MD,' MAMORU ISEMURA, PHD,t MINORU NOMOTO, MD,' CHUlCHl SEKINE, MD,' KENTAROU IGARASHI, MD,' AND FUMlHlRO ICHIDA, MD* ...
The Case of the Silent Abdominal Mass and Elevated α-Fetoprotein Level in an Infant A 9-month-old boy is admitted to the hospital after a right upper quadrant (RUQ) abdominal mass was noted during a health supervision visit. His parents voice no concerns other than mild constipation during ...
Persistent increase in alpha-fetoprotein level in a patient without underlying liver disease who underwent curative resection of hepatocellular carcinoma. A case report and review of the literature. World J Surg Oncol. 2012;10:79. Article Google Scholar Bruix J, Sherman M. Management of ...
Alpha-fetoprotein (AFP) is the most widely used biomarker for hepatocellular carcinoma (HCC) surveillance, which is criticized as neither sensitive nor specific in active hepatitis and liver cirrhosis. The aim of this study was to determine the performance of AFP as a tumor ...
Alpha-fetoprotein (AFP) is a glycoprotein that is primarily synthesized by the fetal liver and yolk sac and is found in relatively low levels in other organs [1]. It is important to note that AFP levels in a healthy person usually stabilize after the age of two. Nonetheless, when liver ...