Serum-alpha-fetoprotein in hepatocellular carcinoma. Lancet . 1974; ii: 334–337.Kohn J, Weaver PC. Serum-alpha-1-fetoprotein in hepato- cellular carcinoma. Lancer 1974; 2:334-336.Kohn J, Weaver PC. Serum alpha-
Alpha-fetoprotein (AFP) has been recognized as a key regulator of cell proliferation in hepatocellular carcinoma (HCC). However, whether AFP functions in cancer cell autophagy remains unknown. This study investigated the effects of AFP on autophagy in HCC cells. The role of AFP was studied in ...
Few studies have assessed the relationship between serum alpha-fetoprotein (AFP) and yttrium-90 (Y-90) radioembolization response in hepatocellular carcinoma (HCC). The objective of the study was to evaluate whether peri-procedural serum AFP was correlated with Y-90 therapy response in HCC. Methods...
alpha fetoproteinall‐trans retinoic acidTNF‐related apoptosis‐inducing ligandcaspase‐3hepatocellular carcinoma cellsapoptosisAlthough there is increasing evidence that alpha fetoprotein (AFP) may function as regulatory factor in the growth of tumor cells, the precise mechanism is still unclear. In the ...
Ramucirumab and the controversial role of α-fetoprotein in hepatocellular carcinoma GK Abou-Alfa - 《Lancet Oncology》 被引量: 0发表: 2019年 Systemic Therapy for Hepatocellular Carcinoma: The Issue of Treatment Stage Migration and Registration of Progression Using the BCLC-Refined RECIST Recent ...
Alpha-fetoprotein (AFP) is a major carcinoembryonic proteinproduced by the liver and the yolk sac during fetallife. Since blood AFP levelsare elevatedin more than 70% of hepatocellular carcinoma patients, it is considered a representative marker for this disease. AFP assay is helpful as an adjunc...
Serum alpha-fetoprotein in hepatocellular the prenatal diagnosis of neural tube defect,'932a0nd for the differential diagnosis of HCC and carcinoma meta- carcinoma. Cancer 1977; 40:779-783. 6. Alpert E, Feller ER. Alpha-fetoprotein (AFP) in benign liver dis- eases: Evidence that norma...
Alpha-fetoprotein (AFP) is the most widely used biomarker for hepatocellular carcinoma (HCC) surveillance, which is criticized as neither sensitive nor specific in active hepatitis and liver cirrhosis. The aim of this study was to determine the performance of AFP as a tumor ...
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Alpha-fetoprotein (AFP) is a well-established biomarker for hepatocellular carcinoma (HCC). Here, we investigated the acetylation state of AFP in vivo. AFP acetylation was regulated by the acetyltransferase CBP and the deacetylase SIRT1. Acetylation of AFP at lysines 194, 211, and 242 increased...