Colon specific delivery of prednisolone-appended-cyclodestrin conjugate: Alleviation of systemic side effect after oral administration. J Controlled Release. 79(1-3): 103-112.Yano H,Hirayama F,Kamada M,et al.Co
Alpha Cyclodextrin is defined as a type of cyclodextrin with a toroid cone structure composed of six glucopyranoside units, which has a hydrophobic core and a hydrophilic exterior. It is used to enhance the solubility and bioavailability of hydrophobic drug molecules through noncovalent interactions. ...
doi: 10.1128/IAI.00115-09 [129] Ragle BE, Karginov VA, Bubeck Wardenburg J (2010) Prevention and treatment of Staphylococcus aureus pneumonia with a beta-cyclodextrin derivative. Antimicrob Agents Chemother 54: 298-304. doi: 10.1128/AAC.00973-09 [130] Bubeck Wardenburg J, Schneewind O (2008...
Tamoxifen citrate, olaparib or saline controls containing 10% (w/v) 2-hydroxy-propyl-betacyclodextrin (Sigma) were injected intraperitoneally into the mice every morning in a volume of 0.2 ml. Mice weight and tumor growth were monitored every 3 days by measuring the tumor length (L) and ...
Alpha Prime Supps Pre-Workout RTD has a whopping 405 milligrams caffeine, 8 grams citrulline malate, and amplifies it with the novel CitraPeak NO booster!
The alpha-hemolysin (AHL) nanochannel is a non-selective channel that allows for uncontrolled transport of small molecules across membranes leading to cell death. Although it is a bacterial toxin, it has promising applications, ranging from drug delivery systems to nano-sensing devices. This study ...
α-Cyclodextrin has the lowest hydrogen bond strengths. The cavities of three cyclodextrins have different diameters, depending on the number of glucose units. The side rim depth is the same for all three (at about 7.9 Å). The diameter of the internal cavity of α-cyclodextrin, 4.7–5.3 ...
Exemplary excipients that may be formulated with clonidine in addition to the biodegradable polymer include but are not limited to MgO (e.g., 1 wt. %), 5050 DLG 6E, 5050 DLG 1A, mPEG, TBO-Ac, mPEG, Span-65, Span-85, pluronic F127, TBO-Ac, sorbital, cyclodextrin, maltodextrin, ...
Injection related side effects occur with the same frequency but moxisylyte results in more systemic side effects and alprostadil results in more painful and prolonged erections. Patients and partners are significantly more satisfied with alprostadil alpha-cyclodextrin....
20030134824 Beta-cyclodextrin dimers and phthalocyanines and uses thereof 2003-07-17 Breslow et al. 6548249 Fusions of scaffold proteins with random peptide libraries 2003-04-15 Anderson et al. 6534061 Tumor necrosis factor receptor homologs and nucleic acids encoding the same 2003-03-18 Goddard et...