Alpha-1抗胰蛋白酶缺乏症的英文名字是Alpha-1 antitrypsin deficiency。基因解码表明:Alpha-1抗胰蛋白酶缺乏症是一种遗传性疾病,与基因突变密切相关。Alpha-1抗胰蛋白酶是一种由SERPINA1基因编码的蛋白质,它在肝脏中合成并通过血液循环分布到全身。该蛋白质的主要功能是
Alpha1-antitrypsin (AAT) deficiency is a common genetic deficiency, but not all with this deficiency develop disease. One deficient genetic type, PI Z, is the major deficiency type, with homozygous PI ZZ individuals at increased risk for disease. Lung disease, specifically emphysema, is the ...
Alpha-1 antitrypsin(抗胰蛋白酶)deficiency is a genetic disorder(遗传病)in which a protein called alpha-1antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺和肝脏...
genetic model of alpha-1-antitrypsin deficiency. chinese.eurekalert.org 圣路易大学儿童医学系塔克曼博士(Jeffrey Teckma)所领导的研究团队,证实了甲一型胰蛋白酵素抑 制剂 缺陷 动 物模 式中有氧化压力的产生。 chinese.eurekalert.org [...] and registered as having originated from the Liberian Camp ...
【1】Serban KA, Pratte KA, Strange C, Sandhaus RA, Turner AM, Beiko T, Spittle DA, Maier L, Hamzeh N, Silverman EK, Hobbs BD, Hersh CP, DeMeo DL, Cho MH, Bowler RP. Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary...
alpha 1-Antitrypsin Deficiency α1抗胰蛋白酶缺乏症文献(pubmed) 以下为句子列表:英文: Purification and biological activity of recombinant thymosin alpha1中文: 重组胸腺素α1的分离纯化和活性测定 英文: The optimization of the recombinant thymosin alpha1’s fermentation conditions中文: 重组胸腺素α1在...
Alpha-1-antitrypsin deficiency (AATD) is a rare genetic disorder associated with the development of liver and lung disease. AAT is a 52-kD glycoprotein, produced mainly by hepatocytes and secreted into the blood. Agglomeration of the AAT-protein in hepatocytes can result in liver disease. Exposur...
Alpha1-antitrypsin deficiency (AATD) was first described by Laurell and Eriksson in 1963. Laurell noted the absence of the band of alpha1- protein in 5 of 1500 serum protein electrophoreses (SPEP) submitted to his laboratory in Sweden.
ALPHA 1 ANTITRYPSIN DEFICIENCY IN THE PATHOGENESIS (OF BRONCHOPULMONARY DYSPLASIABronchopulmonary Dysplasia (BPD) is a major cause of neonatal respiratory morbidity and mortality. The pathophysiology of BPD may be related to an absence of the antiprotease alpha 1 anti-trypsin (αLat) in pulmonary ...
Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of a1AT deficiency, describes the a1AT gene and its promoter, and details specific therapies to ...