The amino acid sequence of the a- and h- globin chains of hemoglobin from the Aldabra giant tortoises, Geo- chelone gigantea. Zool. Sci. 18, 515 - 526.Shishikura F, Takami K (2001) The amino acid sequecences of the α- and β-globin chains of hemoglobin from the Aldabra giant ...
Separation of the alpha- and beta-chains of globins by means of starch-gel electrophoresis.HEMOGLOBIN/chemistryTHE investigation of the molecular weight and the electrophoretic behaviour of globins at p H. 2–4 has led to a better understanding of the structure of the hæmoglobin molecule. ...
(1971). Alpha and beta globin messenger ribonucleic acid. Different amounts and rates of initiation of translation. J. Biol. Chem. 246, 7131-7138.Lodish, H.F., 1971. Alpha and beta globin messenger ribonucleic acid. Different amounts and rates of initiation of translation. J. Biol. Chem....
Alpha thalassemia is caused by reduced or absent synthesis of alpha globin chains, and beta thalas- semia is caused by reduced or absent synthesis of beta globin chains. Imbalances of globin chains cause hemolysis and impair erythropoiesis. Silent carriers of alpha thalassemia and persons with ...
Consequently, the excessive free alpha-globin chains precipitate to the erythrocyte membrane, resulting in hemolytic anemia. We have explored post-transcriptional strategies aiming at alpha-globin reduction and beta-globin enrichment on beta(654) (Hbb(th-4)/Hbb(+)) mouse, carrying a human splicing...
Identificationandcharacterizationofadultalpha-andbeta-globin genesandtheirgenomicarrangementinPseudosCiaenaCToCea CHUWuying 1,2,OIANRonghua 1,WANGLianshen 2,YUXiameng 2, YOUZhengiang 2,YULian 2* 1.DepartmentofBiomedicaIEngineering,ZhejiangUniversity,Hangzhou310027,China 2.InstituteofPreventiveVeterinaryMedicine...
Using alpha- and beta-globin cDNAs from the antarctic rockcod Notothenia coriiceps (family Nototheniidae, suborder Notothenioidei), we have probed the ... E Cocca,M Ratnayake-Lecamwasam,SK Parker,... - 《Proceedings of the National Academy of Sciences of the United States of America》 ...
s are a group of inherited hematologic disorders caused by defects in the synthesis of one or more of the hemoglobin chains. Alphathalassemia is caused by reduced or absent synthesis of alpha globin chains, and beta thalassemia is caused by reduced or absent synthesis of beta globin chains....
Each globin chain gene guides the RBC to make a specific globin chain; the globin chains match with a heme and then assemble into a complete Hb molecule. Hemoglobin disorders are of two main types: structural and synthetic. Structural hemoglobinopathies are due to a change in the amino acid...
Under these conditions, both alpha and beta globin chains reduced the spectrin-binding capacity of the IOVs by approximately 45% (alpha 46 +/- 7%, beta 43 +/- 6%) whereas haemoglobin A had no effect. Unlike IOVs, spectrin isolated from membranes exposed to alpha or beta globin chains ...