Background: Gamma-aminobutyric acid type A (GABA A ) receptors in the brain are modulated by chronic ethanol exposure via the regulation of their function... S Papadeas,AC Grobin,AL Morrow - 《Alcoholism Clinical & Experimental Research》 被引量: 257发表: 2001年 加载更多来源...
Progesterone (0.5 and 1.0 mg/kg) also elevated tailflick latencies above vehicle controls, while 2.0 and 4.0 mg/kg produced intermediate effects. In Expt. 2, 3 alpha-Diol (3 alpha-Diol:BSA) and P (P:BSA) conjugated to bovine serum albumin (BSA) were applied to the medial basal ...
Widespread α3KD in TRN determines elevated NREM delta power Selective deletion of α3 subunits in TRN PV neurons requires the combination of selective expression of Cas9 in PV neurons and sgRNA targeting α3 subunits in the same cells. mCherry (red; marker of sgRNA) was expressed in the maj...
Knockdown of GCN2 in dopaminergic neurons reduced this aversive response in larvae via regulation of gamma-aminobutyric acid (GABA) signaling [61,62]. These common findings in vertebrates and invertebrates highlight that central GCN2 signaling is an ancient nutrient-sensitive pathway for maintaining ...
Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic inter- actions with dopamine neurons. J Comp Neurol 448: 360–372. Darracq L, Blanc G, Glowinski J, Tassin ...
(II) whose R′ residue comprises at least two C atoms. A particularly elevated proportion of the organoleptically valuable aldehydes of type (I) or (II) may, for example, be obtained by a production method in which, in a first step, terminal olefins are isomerized to yield interior ...
(Figure 5a). Although cocaine significantly elevated extracellular DA in the medial NAc shell in each treatment group, both doses of intra-NAc terazosin attenuated the effects of cocaine (Figure 5a). Two-way repeated measures ANOVA showed a significant effect of time (F(11, 198)=15.44,p<...
However, the differential effects of alpha(S1)-CH on electroencephalographic wave patterns and its effects on the protein levels of gamma-aminobutyric acid A (GABA(A)) receptor subtypes in hypothalamic neurons are not well understood. We found alpha(S1)-CH (120, 240 mg/kg) increased sleep ...
Finally, anomalies in memory-related EEG oscillations could also be partially due to disruption of fast synap- tic inhibition mediated by γ-aminobutyric acid (GABA) neurons. Extensive research suggests that GABAergic neurons play a critical role in generating network synchrony in general46 and ...
It is well known that fluoxetine (Fluox), a selective serotonin reuptake inhibitor, increases the brain content of allopregnanolone (AP), a potent neuroactive steroid that positively modulates the action of gamma-aminobutyric acid (GABA) at the GABA type A receptors, but the influence of Fluox...