Alpha-2antagonistantidepressantsare medications prescribed to treat depression. Alpha-2agonistantidepressants work on thecentral nervous systemto increase the levels and modulate the activity of norepinephrine andserotonin, chemical messengers (neurotransmitters) released by nerve cells (neurons). Mood regulation...
-receptors, isoproterenol-induced drinking (IID), would be reduced by subacute antidepressant/ α 2 -antagonist treatmentThe coadministration of typical (e.g., imipramine) or atypical (e.g., mianserin) antidepressants with yohimbine or piperoxan twice daily for four consecutive days reduced IID. ...
alpha-actinin-2 Alpha-actinin-2-associated LIM protein alpha-actinin-3 alpha-actinin-4 Alpha-adaptin A Alpha-adaptin C alpha-adaptin C; Huntingtin interacting protein J alpha-adducin alpha-adrenergic alpha-adrenergic agonist alpha-adrenergic antagonist ...
Therefore, we have here studied the LC neuronal responsiveness to administration of the alpha 2-adrenoceptor antagonist idazoxan (IDA) after both short-term and long-term imipramine (IMI) administration. METHODS: Rats were treated for different periods with systemic IMI. In these rats, basal activit...
Quercetin induced a significant behavioral despair, which was abrogated with pretreatment with yohimbine, an alpha(2) adrenoceptor antagonist, and imipramine, a tricyclic antidepressant. The results of the study support the contention that quercetin utilizes presynaptic alpha(2) adrenoceptors in eliciting ...
Indicate a beta-receptor antagonist with intrinsic sympathomimetic activity: a) Propranolol b) Oxprenolol c) Metoprolol d) Carvedilol Which of the following NSAIDs is a selective COX-2 inhibitor? a) Piroxicam b) Indomethacin c) Celecoxib d) Diclofenac ...
The risk of fall and fracture with the initiation of a prostate-selective α antagonist: A population based cohort study. BMJ. 2015;351: h5398. Article PubMed PubMed Central Google Scholar Seo GH, Shim SR, Lee HW, Kim JH, Chun DI, Kim HJ, et al. Risk for hip fracture due to ...
The risk of fall and fracture with the initiation of a prostate-selective α antagonist: A population based cohort study. BMJ. 2015;351: h5398. Article PubMed PubMed Central Google Scholar Seo GH, Shim SR, Lee HW, Kim JH, Chun DI, Kim HJ, et al. Risk for hip fracture due to ...
Agomelatine is a melatonergic MT1/MT2 agonist and a serotonin (5-HT) 5-HT2C antagonist. The effects of 2-day and 14-day administration of agomel... Franck,Chenu,Mostafa,... - 《Neuropsychopharmacology》 被引量: 97发表: 2012年 Agomelatine (S20098) modulates the expression of cytoskeletal ...
The term “antagonist” in the present context refers to a substance capable of inhibiting the effect of a receptor agonist. Full agonists bind (have affinity for) and activate a receptor, displaying full efficacy at that receptor. “Partial agonists” in the present context are peptides able ...