Definition 伪 1 -Antitrypsin is a glycoprotein of hepatic derivation, it constitutes an important serine protease inhibitor, responsible for the regulation of various serine proteinases, including trypsin, chymotrypsin, collagenase, elastase,cathepsin G, factor VIII, and kallicrein. Its deficiency has ...
but one phenotype, PiZZ, is responsible for nearly all cases of AAT deficiency emphysema and liver disease. PiZZ phenotype serum levels range from 3.4-7 µmol/L, about 10-20% of the reference range levels. Other phenotypes associated with alpha1-antitrypsin emphysema and liver disease include ...
Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase,plasmin,collagenase,thrombin,leucocyte proteases,trypsin,chymotrypsin,and plasminogen activator. Clinically,its deficiency is associated with two major...
No. Trypsin Elastase Chymotrypsin mg/100 ml (M±2S.D.) G.C., E.C. Parents Normal children Normal adults Diseased controls 0.46; 0.34 0.25; 0.18 0.29; 0.28 18.0; 9.0 0.78; 0.71 0.37; 0.39 0.75, 0.65 185; 186 1.13 ± 0. 22 0 .66 ± 0. 14 0.99 ± 0.31 280 ± 94 1.07 ± ...
alpha-chymotrypsin-induced glaucoma alpha-cortol alpha-cortolone alpha-dextrin endo-1,6-alpha-glucosidase alpha-d-galactosidase alpha-d-glucosidase alpha-farnesene alphafetoprotein Alpha-fetoprotein Alpha-fetoprotein analysis Alpha-Fetoprotein Test alpha-fucosidase Alpha-galactosidase A deficiency Alphagan alph...
Noun1. alpha decay- radioactive decay of an atomic nucleus that is accompanied by the emission of an alpha particle radioactive decay,disintegration,decay- the spontaneous disintegration of a radioactive substance along with the emission of ionizing radiation ...
展开 关键词: Animals Cattle Humans Pulmonary Emphysema alpha 1-Antitrypsin Deficiency Chymotrypsin alpha 1-Antitrypsin Serine Proteinase Inhibitors Blotting, Western Electrophoresis, Polyacrylamide Gel DOI: http://dx.doi.org/ 被引量: 34 年份: 1997 收藏...
I speculated that a deficiency of protease inhibitor may subject the duodenal or gastric mucosa to ulceration by gastric pepsin, implying that alpha1-antitrypsin may inhibit pepsin as well as trypsin, chymotrypsin, leukocytic proteases, elastase and thrombin. Our subsequent studies, with the support...
Alpha antitrypsin deficiency has been associated with emphysema in man; industrial workers exposed to cadmium for prolonged periods of time also develop emphysema. In the present studies, the authors attempted to determine the effect of cadmium and other trace metals (lead, zinc, nickel and iron) ...
Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these ...