This paper reviews the development of a-blockade, the therapeutic efficacy of prazosin, the prototype 伪-1 blocker, and the rationale for the once-daily antihypertensive compounds, terazosin and doxazosin. These drugs offer a useful alternative to first- or second-line therapy in suitable ...
Alpha1-adrenoceptor antagonists (alpha1-blockers) are currently used as first-line drugs for the treatment of benign prostatic hyperplasia (BPH). However, ... T Imamura,K Ishii,H Kanda,... - 《Clinical & Experimental Medicine》 被引量: 1发表: 2010年 The efficacy and safety of alpha-1 ...
Noun1. alpha-adrenergic blocker- any of various drugs that block alpha-adrenergic receptors; used in treating benign prostatic hyperplasia; relaxes the muscles of the prostate and bladder alpha blocker,alpha-adrenergic blocking agent,alpha-blocker ...
Vaccination against influenza in rheumatoid arthritis: the effect of disease modifying drugs, including TNF alpha blockers. To assess the efficacy and safety of vaccination against influenza virus in patients with rheumatoid arthritis, with special emphasis on the effect of dise... I Fomin,D Caspi,...
OBJECTIVES: To determine the safety and efficacy of intermittent alpha-blocker therapy in men with lower urinary tract symptoms (LUTS) in a prospective study. Alpha-blockers have been demonstrated to be safe and effective in the treatment of men with LUTS. To date, the role of varying dosing...
The present invention relates to a method of preventing and treating chronic hepatitis and other liver diseases comprising administering a blocker of Light, LTα1β2, LTα2β1 or LTβR, and the use of such blockers in said prevention and treatment and in the manufacture of medicaments for ...
We select and prescribe various alpha-blockers in real-life clinical practice, but the study data regarding which drugs are actually prescribed and how these trends are changing over time is insufficient. The analysis of α-blocker prescription patterns is important to assess medication adherence, ad...
Stribild should be administered under fed conditions to optimize drugs exposure. Here we assessed to what extent this advice is applied in the real life scenario by therapeutic drug monitoring in 75 HIV-infected patients given Stribild-based antiretroviral therapy. Fifty-three percent of our patients...
There was no statistically significant difference between the drugs in terms of percent improvements in IPSS and Q max with alpha-blocker treatment. No untoward effect except for transient dizziness in one case with terazosin treatment was encountered. Conclusion Different alpha-blockers, which are ...
induces prostate apoptosis in patients with benign prostatic hyperplasia (BPH).[1] in this study, to determine whether this apoptotic response was mediated by alpha1 adrenoceptor-dependent mechanism or was specific to doxazosin, we examined the effect of another alpha1 blocker, terazosin, in addition...