alpha-1-antitrypsinbile ductsA child is reported whose alpha‐1 ‐antitrypsin phenotype is SZ and who has chronic cholestatic liver disease that began in the neonatal period. Liver biopsy demonstrated paucity of the interlobular bile ducts, marked hepatocellular deposition in periportal areas of PAS...
Alpha-1抗胰蛋白酶缺乏症的英文名字是Alpha-1 antitrypsin deficiency。基因解码表明:Alpha-1抗胰蛋白酶缺乏症是一种遗传性疾病,与基因突变密切相关。Alpha-1抗胰蛋白酶是一种由SERPINA1基因编码的蛋白质,它在肝脏中合成并通过血液循环分布到全身。该蛋白质的主要功能是
In this case, testing revealed that the patient was also heterozygous for alpha-1-antitrypsin (A-1-AT) with the phenotype of PI<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mo>⁎</mml:mo></mml:mrow></mml:math>EM. This mutant phenotype has...
Severe alpha-1-antitrypsin (AAT) deficiency, phenotype Pi ZZ, is a rare condition with an estimated prevalence of 1/4500 individuals in Spain. Given this l... M Miravitlles,R Vidal,JC Barros-Tizón,... - 《Respiratory Medicine》 被引量: 94发表: 1998年 Evaluation of danazol therapy for...
Diagnosis of alpha-1 antitrypsin deficiency often begins with a chest X-ray or Chest CT to look for hyperinflated(过度膨胀) lungs or evidence of damaged lung tissue. 一般诊断的话肺就看胸片或者CT,或者找到一些肺损伤的证据 In addition, pulmonary function testing can be used to measure how quickl...
genetic model of alpha-1-antitrypsin deficiency. chinese.eurekalert.org 圣路易大学儿童医学系塔克曼博士(Jeffrey Teckma)所领导的研究团队,证实了甲一型胰蛋白酵素抑 制剂 缺陷 动 物模 式中有氧化压力的产生。 chinese.eurekalert.org [...] and registered as having originated from the Liberian Camp ...
Severe alpha‐1‐antitrypsin deficiency increases the risk of venous thromboembolism Background Severe alpha-1-antitrypsin deficiency (AATD), phenotype PiZZ, is associated with increased risk of liver disease and chronic obstructive pulmona... N Basil,M Ekstroem,E Piitulainen,... - 《Research & ...
Alpha-1 antitrypsin(抗胰蛋白酶)deficiency is a genetic disorder(遗传病)in which a protein called alpha-1antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺和肝脏...
ALPHA 1 ANTITRYPSIN DEFICIENCY IN THE PATHOGENESIS (OF BRONCHOPULMONARY DYSPLASIABronchopulmonary Dysplasia (BPD) is a major cause of neonatal respiratory morbidity and mortality. The pathophysiology of BPD may be related to an absence of the antiprotease alpha 1 anti-trypsin (αLat) in pulmonary ...
doi:10.1080/21548331.1971.11706032HarveyUniversityL.UniversitySharpUniversityInformaworldHospital PracticeSharp H. L. Alpha-1-antitrypsin deficiency. Hosp Pract 1971 ; 6: 83 [Taylor & Francis Online]