Alpha-1-antitrypsin deficiency (AATD) is a rare genetic disorder associated with the development of liver and lung disease. AAT is a 52-kD glycoprotein, produced mainly by hepatocytes and secreted into the blood. Agglomeration of the AAT-protein in hepatocytes can result in liver disease. Exposur...
Alpha-1-Antitrypsin Deficiency with Severe Panniculitis: A Histopathologic and Immunopathologic Study of Four Cases. An abstract is unavailable. This article is available as a PDF only. Su,PD W.,Smith,... - 《American Journal of Dermatopathology》 被引量: 62发表: 1987年 Alpha-1-antitrypsin ...
alpha‐1‐antitrypsin deficiencyclassical form of α1‐antitrypsin deficiency ‐ target organ injury by loss‐of‐function and gain‐of‐toxic function mechanismscellular pathobiology of α1‐antitrypsin deficiency ‐ retention of mutant Z α1‐antitrypsin...
Get PDF (804K) Keywords: Alpha 1-antitrypsin deficiency; PiSZ phenotype; pancreatitis; elastase; ERCP Abstract: An 18-year-old female with PiSZ phenotype alpha 1-antitrypsin deficiency presented with pancreatitis and a pancreatic pseudocyst. There were no other causative factors. Deficiency of alpha...
Alpha-1-antitrypsinProteaseAntiproteaseLiver diseaseChronic obstructive pulmonary disease (COPDTwo disparate disease states—an adult form of emphysema and a childhood form of liver cirrhosis—have been linked to an inherited absence of this antienzyme. In their severe, homozygous forms, both conditions...
Alpha1-antitrypsin deficiency (AATD) was first described by Laurell and Eriksson in 1963. Laurell noted the absence of the band of alpha1- protein in 5 of 1500 serum protein electrophoreses (SPEP) submitted to his laboratory in Sweden.
Alpha1-antitrypsin deficiency (AATD) was first described by Laurell and Eriksson in 1963. Laurell noted the absence of the band of alpha1- protein in 5 of 1500 serum protein electrophoreses (SPEP) submitted to his laboratory in Sweden.
【Osmosis】α-1抗胰蛋白酶缺乏症 Alpha-1 Antitrypsin Deficiency(中英字幕) 996 1 1:09 App 丝裂原活化蛋白激酶-MAPK(mitogen-activated protein kinase)-动画 16 -- 2:05 App 脂肪酸氧化缺乏 Fatty acid oxidation deficiency_PTH 8082 3 2:16 App 胰腺之歌(英文字幕) 757 -- 17:48 App (搬运油管...
ALPHA 1 ANTITRYPSIN DEFICIENCY IN THE PATHOGENESIS (OF BRONCHOPULMONARY DYSPLASIABronchopulmonary Dysplasia (BPD) is a major cause of neonatal respiratory morbidity and mortality. The pathophysiology of BPD may be related to an absence of the antiprotease alpha 1 anti-trypsin (αLat) in pulmonary ...
Alpha-1 antitrypsin (AAT) testing is performed to detect a deficiency of the AAT protein. The AAT protein is involved in protecting the lungs and liver from damage. AAT deficiency is an inherited disorder that heightens the risk ofchronic obstructive pulmonary disorder (COPD), a serious lung co...