1-antitrypsin deficiency (disorder), alpha-1-Antitrypsin deficiency (disorder), alpha-1-Antitrypsin deficiency, Alpha-1-antitrypsin deficiency, Alpha-1 anti-trypsin deficiency, Alpha-1 proteinase inhibitor deficiency, Alpha-1-antitrypsin def, A-1ATD, A1AD, AAT deficiency, alpha 1-Antitrypsin ...
Introduction:Alpha 1-antitrypsin deficiency (AATD) is a genetic disorder which reduces serum alpha 1-antitrypsin (AAT or alpha1-proteinase inhibitor, A1PI) and increases the risk of chronic obstructive pulmonary disease (COPD). Management strategies include intravenous A1PI augmentation, and, in some...
Alpha-1-antitrypsin deficiency and periodontitis, a pilot study. The aim of this study was to investigate if periodontal parameters and elastase in gingival crevicular fluid (GCF) are different in alpha-1-antitrypsin def... Viveca,Wallin-Bengtsson,Eeva,... - 《Swedish Dental Journal》 被引量...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Alphagan Brimonidine Ophthalmology An alpha-2 agonist for treating open-angle glaucoma. See Open angle glaucoma. McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc. ...
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimm... Invasive insulitis is a destructive T cell-dependent autoimmune process directed against insulin-producing beta cells that is central to the pathogenesis o... M Koulmanda,M Bhasin,L Hoffman,... - 《...
Acid Glycoprotein,α-1ActinActininAdipocyte Fatty Acid Binding Protein [ALBP]Adipogenesis AssayAdipolysisAdiponectin [ACRP30]Adipose Differentiation-related ProteinAgouti [ASP]Agouti Related Protein[AGRP]AlbuminAlcohol DehydrogenaseAldolaseAlkaline PhosphataseAllergyInflammationαFetoProtein [AFP]α-1-Antitrypsin [...
(MERB), 3500 N. Broad Street, Philadelphia, PA, 19140, USA A R T I C L E I N F O Keywords: Alpha 1 Antitrypsin Alpha 1 Antitrypsin Def i ciency Diagnostic tests Mutation Novel variants SERPINA1 A B S T R A C T Alpha 1 Antitrypsin Def i ciency (AATD) is a rare condition ...
The cytotoxic potential of defensins is mitigated by the presence of serum, which contains several proteins that bind defensins, including α2-macroglobulin, α1-antitrypsin, α1-antichymotrypsin, antithrombin 3 and antiplasmin. Some defensins cause the degranulation of mast cells in vitro and many ...
Alpha1-antitrypsin defciency-related liver disease is therefore caused by a gain-of-function mechanism due to accumulation of the mutant Z alpha1-antitrypsin (ATZ) and is a key example of an disease mechanism induced by protein toxicity. Intracellular retention of ATZ triggers a complex injury ...
Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis[J] . David Lomas,Dickens.Drug Design, Development and Therapy . 2011 (defa) Dickens JA, Lomas DA. Why has it been so difficult...