Alpha-1 antitrypsin and liver disease: mechanisms of injury and novel interventions [J]. Expert Rev Gas- troenterol Hepatol, 2014, 28:1-8 [Epub ahead of print].Teckman, Jeffrey H.,Mangalat, Nisha. Alpha-1 antitrypsin and liver disease: mechanisms of injury and novel interventions[J]....
ALPHA ANTITRYPSIN (α1AT) AND LIVER DISEASEPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro techniques relevant to ...
Crystal RG.Alpha 1 - antitrypsin deficiency, emphysema, and liver disease;genetic basis and strategies for therapy.The Journal of Clinical Investigation.1990... RG Crystal - 《Journal of Clinical Investigation》 被引量: 616发表: 1990年 The liver in adolescents with alpha 1-antitrypsin deficiency....
alpha]1-Antitrypsin deficiencyliverIn an effort to characterize the hepatic abnormality in patients with alpha1-antitrypsin deficiency, three unrelated children with the disorder (Pi types ZZ and SZ), two heterozygous parents (Pi type MZ), and three normal subjects (Pi type MM) were studied. As...
The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Rise in alpha 1 antitrypsin occurs as an acute phase response to tissue necrosis and inflammation.应用类型 Western blot免疫原 Human alpha1 antitrypsin (Cat # 7294)...
Alpha 1-antitrypsin deficiency is an inherited metabolic disorder that predisposes the affected individual to chronic pulmonary disease, in addition to chronic liver disease, cirrhosis, and hepatocellular carcinoma. Just over one-third of genetically susceptible adult patients with the most severe phenotype...
Alpha-1 antitrypsin(抗胰蛋白酶)deficiency is a genetic disorder(遗传病)in which a protein called alpha-1antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺和肝脏...
Using isoelectric focusing in polyacrylamide gel, alpha-1-antitrypsin phenotyping was carried out in 1,000 normal Nigerians and in 25 with hepatocellular carcinoma, 17 with cirrhosis of the liver and 193 with neonatal jaundice. The percentage frequency of the homozygous alpha-1-antitrypsin deficiency...
Alpha-1-antitrypsineAlpha-1-antitrypsinedoi:[90-10-0100] -Doi : 10.1016/S0000-0000(09)48236-6Alpha-1-antitrypsin deficiency is the most common inborn error of metabolism leading to liver transplantation, and the second cause of liver transplantation in children after biliary atresia. The authors...
P. : lmmunohistochemical demonstration of alpha- I-antitrypsin in liver tissue. A methodological investigation. Acta path. microbiol. scand. Sect. A 88: 299-306,1980.Clausen PP (]980) Immunohistochemical demonstration of cq- antitrypsin in liver tissue. Acta Path Microbiol Scand Sect A 88:299...