Bazan-Socha S, Zuk J, Plutecka H et al (2012) Collagen receptors α1β1 and α2β1 integrins are involved in transmigration of peripheral blood eosinophils, but not mononuclear cells through human microvascular endothelial cells monolayer. J Physiol Pharmacol 63:373–3...
Receptors are the specific cellular structures with which drugs and hormones first interact (Lefkowitz, 1976a). They may be located at the cell surface or within the cell and they perform two important functions. They first bind drug or hormone molecules through some complementarity of chemical str...
Influence of beta-adrenergic agonists and antagonists on the GH-releasing effect of Hexarelin in man Beta-adrenergic receptors mediate the inhibitory influence of cathecolamines on GH secretion, probably via the stimulation of hypothalamic somatostatin rel... E Arvat,L Gianotti,J Ramunni,... - ...
2.2.1Retinoic acid receptor (RAR) Retinoic acid receptors play important roles in mediating the actions ofretinoic acidoncell differentiationand proliferation during vertebrate development. There are threeRARreceptor subtypes (RAR α, β, γ) encoded by three separate genes (Benbrook et al., 19...
We identified that binding of COL11A1 to its receptors, α1β1 integrin and discoidin domain receptor 2 (DDR2), activates Src-Akt-AMPK signaling to increase the expression of both fatty acid synthesis and oxidation enzymes, although DDR2 seems to be the predominant receptor. Inhibition of ...
HCoV-229E and HCoV-NL63 are both alphacoronaviruses and although closely related, they have evolved to use two different receptors, aminopeptidase N (APN) and angiotensin converting enzyme 2 (ACE2), respectively8, 9. The more distantly related betacoronaviruses, HCoV-OC43 and HCoV-HKU1, are...
CONCLUSION: ADRB1 and ADRA2C polymorphisms synergistically influence the ejection fraction response to beta-blocker therapy of heart failure patients. 展开 关键词: Humans DNA Primers Adrenergic beta-Antagonists Stroke Volume Receptors, Adrenergic, beta-1 Amino Acid Substitution Ventricular Function, Left ...
To assess the primary target for TGF alpha, we examined expression of receptors for TGF alpha (epidermal growth factor receptor) and found receptors to be localized to the apical surface of the epithelial cells of the ventral prostate gland. We next investigated a potential developmental role for...
Optimal concentrations of PDGF-AB (1 ng/mL) was shown to upregulate BMPR-1B mRNA by 2.4 fold.160 Two types of PDGF receptors (R) have been identified: platelet-derived growth factor receptor, alpha polypeptide PDGFRA and platelet-derived growth factor receptor, beta polypeptide PDGFRB. Th...
5-HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensiti- zation to opiates and psychostimulants. Eur J Neurosci 20: 3073–3084. Berridge CW, Stratford TL, Foote SL, Kelley AE (1997). Distribu- tion of dopamine beta-hydroxylase-...