Recently we provided a new interpretation that increased serum ALP in dogs is not adverse if no hepatotoxic finding coexists in the analysis of toxicity studies of over 200 pesticides evaluated in Japan (Yokoyama et al., 2019). We also proposed a decision tree to evaluate the adversity of ...
Hematologic, biochemical, and adverse effects on the 13 patients completing the 0.05 mg/kg and 0.1 mg/kg doses were analyzed. Assessments included the change from baseline. The mean baseline values for HIV-1 RNA, CD4+, and CD8+ T-cell numbers are shown in Table 1. ...
J. Stokes
An increase in serum alkaline phosphatase (ALP) activity is a common laboratory finding in dogs. It is typically used as a diagnostic marker for cholestatic liver disease. However, increased ALP activity has a high sensitivity (86%) but poor specificity (49%) for canine liver disease.Susan E...
In all species the rate of aromatic hydroxylation reached a plateu above 50 μM of alprenolol in contrast to the rate of desisopropylation, where consistent saturation level was not obtained. The Km-values for the aromatic hydroxylation in the guinea-pig and man, 2,7 μM and 1.3 μM ...