The incidence of acutegraft-versushost-disease (GVHD and the transplant related mortality (TRM)were higher in the MUD group, while eight relapses occurred in eachgroup. The relapse rate was lower in children with chronic GVHD. Theseresults support the use of MUDs when a sibling dono...
These complications included: ITP, AIHA, autoimmune pneumonitis, nephritic syndrome, TTP and Kaposi sarcoma. The mortality from these complications was 80% (4 out of 5 patients). 4 patients developed blast crisis post transplant; 2 patients have died; and the others are currently in CR post ...
Allogeneicstem cell transplantationis an established treatment modality for a variety of hematologicmalignancies. Unfortunately, it carries a high risk of complications and toxicities related to the intensive preparative regimen which is traditionally used for pre-transplant myeloablation and thegraft versus ...
Maffini E, Festuccia M, Brunello L, Boccadoro M, Giaccone L, Bruno B (2017) Neurologic complications after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 23:388-397.Neurologic complications after allogeneic hematopoietic stem cell transplantation. Maffini E,Festuccia ...
One patient relapsed 8 months post transplant. Two patients (9%) developed Veno-occlusive disease (VOD) liver. One patient had haemorrhagic cystitis. Four patients (18%) had post transplant infectious complications, which included pseudomonas septicemia, aspergillosis, tuberculous pleural effusion and ...
REFERENCES Baird K, Fry TJ, Steinberg SM, Bishop MR, Fowler DH, Delbrook CP, Humphrey JL, Rager A, Richards K, Wayne AS, Mackall CL (2012) Reduced-intensity allogeneic stem cell transplantation in children and young adults with ultrahigh-risk pediatric sarcomas. Biol Blood Marrow Transplant ...
We review previous studies of nutritional support in allotransplant recipients and discuss possible molecular mechanisms involved in metabolic immunoregulation and the development of post-transplant immunemediated complications. 展开 关键词: Allogeneic Stem cell transplantation graft versus host disease T cell ...
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is the only curative treatment for myelofibrosis. Major improvements in the field, such as the introduction of reduced intensity conditioning regimens, have made transplant a better tolerated treatment that can be offered to older patients an...
The NRM rate continued to increase in the second year after transplantation, probably due to chronic GVHD and infectious complications. The NRM rate was similar in sibling and unrelated transplants, as reported previously [24]; however, our data did not confirm the increased NRM risk in ...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the most important treatment option for malignant and non-malignant hematological disorders [1]. The ability to perform a hematopoietic stem cell transplant depends on the availability of matched sibling donor (MRD) or unrelated donor (...