Increased immune activity leads to increased production of IL-2, IL-4, IL-5, IL-6, IL-10, IFN-γ, and tumor necrosis factor α. Scurfy T cells are less sensitive than healthy controls to cyclosporine and to inhibitors of tyrosine kinases such as herbimycin A and genistein.24 Thus, ...
The variety of chemically diverse pharmacologically-active compounds administered to patients is large and seemingly forever growing, and, with every new drug released and administered, there is always the potential of an allergic reaction. The most commonly occurring allergic responses to drugs are the...